Endometriosis Research: From Bench to Bedside

Antonio Simone Laganà, La Rosa, Valentina Lucia, Valentina Lucia
2022 · doi:10.3390/books978-3-0365-2798-7 · W4210334139
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This book summarizes recent basic/translational research on endometriosis, covering diagnosis, treatments, immunology, cell biology, genetics, and epigenetics to improve understanding and management of the disease.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-11-08 · read from full text ⓘ

This publication is a reprint of a special issue that compiles recent studies on the etiology, diagnosis, and management of endometriosis. It covers basic and translational science aspects including immunology, cell biology, genetics, and epigenetics to explore new pathways for future treatment. The book aims to summarize groundbreaking research that may change perspectives on the condition's controversial pathogenesis involving immune, hormonal, and genetic factors. This paper is centrally about endometriosis — specifically serving as a comprehensive review of bench-to-bedside research covering diagnosis, pharmacologic and surgical treatments, and underlying biological mechanisms.

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Abstract

Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but estimates range from 2%–10% of women of reproductive age, to 50% of infertile women. Its etiopathogenesis of endometriosis still remains controversial—immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.This book aims to summarize recent ground-breaking studies that may open new scenarios and change the perspective of the topic, including cutting-edge elements about diagnosis, pharmacologic and surgical treatments, as well as basic/translational science (immunology, cell biology, genetics, and epigenetics) pieces of evidence, to unravel new pathways to follow for the future diagnosis and management of endometriosis, and to improve our current knowledge of its aetiology.
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Endometriosis Research: From Bench to Bedside - ISBN 978-3-0365-2799-4 (Hardback) - ISBN 978-3-0365-2798-7 (PDF) This is a Reprint of the Special Issue Endometriosis Research: From Bench to Bedside that was published in Summary Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but estimates range from 2%–10% of women of reproductive age, to 50% of infertile women. Its etiopathogenesis of endometriosis still remains controversial—immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.This book aims to summarize recent ground-breaking studies that may open new scenarios and change the perspective of the topic, including cutting-edge elements about diagnosis, pharmacologic and surgical treatments, as well as basic/translational science (immunology, cell biology, genetics, and epigenetics) pieces of evidence, to unravel new pathways to follow for the future diagnosis and management of endometriosis, and to improve our current knowledge of its aetiology.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

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