Genetic Polymorphisms and Molecular Pathogenesis of Endometriosis

Vijayalakshmi Kodati; Q. Has

doi:10.5772/28907

Genetic Polymorphisms and Molecular Pathogenesis of Endometriosis

Vijayalakshmi Kodati, Q. Has

In: Endometriosis - Basic Concepts and Current Research Trends · 2012 · doi:10.5772/28907 · W1601219650

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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This review explores genetic polymorphisms and molecular pathogenesis involved in endometriosis, discussing candidate genes and signaling pathways implicated in the disease.

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Abstract

Endometriosis -

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endometriosis

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References (97)

Affected sib-pair analysis in endometriosis via openalex
Allelic loss studies do not provide evidence for the “endometriosis-as-tumor” theory via openalex
Allelotyping of endometriosis with adjacent ovarian carcinoma reveals evidence of a common lineage. via openalex
Analysis of the codon 72 polymorphism of the TP53 gene in patients with endometriosis via openalex
Androgen Receptor Gene Cytosine, Adenine, and Guanine Trinucleotide Repeats in Patients With Endometriosis via openalex
Angiotensin I-converting enzyme ACE 2350*G and ACE-240*T-related genotypes and alleles are associated with higher susceptibility to endometriosis via openalex
Association between human α 2-Heremans Schmidt glycoprotein (AHSG) polymorphism and endometriosis in Korean women via openalex
Association of progesterone receptor gene polymorphism (PROGINS) with endometriosis, uterine fibroids and breast cancer via openalex
Chronic Pelvic Pain via openalex
Cytogenetic studies in endometriosis tissue via openalex
DNA microarray analysis of gene expression profiles in deep endometriosis using laser capture microdissection via openalex
Endometriosis and the development of malignant tumours of the pelvis. A review of literature via openalex
Endometriosis is not associated with or linked to the GALT gene via openalex
Endometriosis-Specific Genes Identified by Real-Time Reverse Transcription-Polymerase Chain Reaction Expression Profiling of Endometriosis Versus Autologous Uterine Endometrium via openalex
EPIDEMIOLOGY OF ENDOMETRIOSIS via openalex
ESHRE guideline for the diagnosis and treatment of endometriosis via openalex
Estrogen receptor-alpha gene (T/C) Pvu II polymorphism in endometriosis and uterine fibroids. via openalex
Estrogen receptor α dinucleotide repeat and cytochrome P450c17α gene polymorphisms are associated with susceptibility to endometriosis via openalex
[Etiology and pathogenesis of endometriosis]. via openalex
Expression of oestrogen receptor-alpha and -beta in ovarian endometriomata via openalex
Genetic Alterations in Microsatellite Marker Sites among Tumor Suppressor Genes in Endometriosis via openalex
Genetics of endometriosis: a role for the progesterone receptor gene polymorphism PROGINS? via openalex
Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis. via openalex
Genomewide Linkage Study in 1,176 Affected Sister Pair Families Identifies a Significant Susceptibility Locus for Endometriosis on Chromosome 10q26 via openalex
Genomewide Linkage Study in 1,176 Affected Sister Pair Families Identifies a Significant Susceptibility Locus for Endometriosis on Chromosome 10q26 via openalex
GSTM1, GSTT1 and CYP1A1 detoxification gene polymorphisms and their relationship with advanced stages of endometriosis in South Indian women via openalex
Heritability and Molecular Genetic Studies of Endometriosis via openalex
High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis via openalex
Human endometriosis-derived permanent cell line (FbEM-1): establishment and characterization via openalex
Increased prevalence of p53 overexpression from typical endometriosis to atypical endometriosis and ovarian cancer associated with endometriosis via openalex
Increase in the number of integrinβ1-immunoreactive monocyte-lineage cells in experimentally-induced adenomyosis in mice via openalex
Is There a Genetic Basis to Endometriosis? via openalex
Lack of Association Between Endometriosis and N-acetyl transferase 1 (NAT1) and 2 (NAT2) Polymorphisms in a Japanese Population via openalex
Lack of association between endometriosis and the<b><i>CYP17 Msp</i></b>A1 polymorphism in UK and Japanese populations via openalex
Lack of association between endometriosis and the CYP17 MspA1 polymorphism in UK and Japanese populations. via openalex
Linkage and association studies of the relationship between endometriosis and genes encoding the detoxification enzymes GSTM1, GSTT1 and CYP1A1 via openalex
Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci. via openalex
Microsatellite DNA assays reveal an allelic imbalance in p16Ink4, GALT, p53, and APOA2 loci in patients with endometriosis via openalex
Molecular mechanisms and biological plausibility underlying the malignant transformation of endometriosis: a critical analysis via openalex
Molecular Pathogenesis of Endometriosis; Toll-Like Receptor-4 A896G (D299G) Polymorphism: A Novel Explanation via openalex
No Association of Endometriosis With Glutathione S-Transferase M1 and T1 Null Mutations in a Japanese Population via openalex
Polymorphic (CAG)n repeats in the androgen receptor gene via openalex
Polymorphism for Transforming Growth Factor Beta 1-509 (TGF-B1-509): Association with Endometriosis via openalex
Polymorphisms in the estrogen receptor β gene but not estrogen receptor α gene affect the risk of developing endometriosis in a Japanese population via openalex
Polymorphisms in the promoter regions of FAS and FASL genes as candidate genetic factors conferring susceptibility to endometriosis via openalex
Preliminary molecular genetic analysis of the Receptor Interacting Protein 140 (RIP140) in women affected by endometriosis via openalex
Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis via openalex
Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis1 via openalex
PROGINS receptor gene polymorphism is associated with endometriosis via openalex
[Relationship between endometriosis and glutathione S-transferase M1, T1 genes of the Uygurs and Hans in Xinjiang]. via openalex
Role of shigella infection in endometriosis: A novel hypothesis via openalex
Steroidal regulation of endometriosis tissue: lack of induction of 17β-hydroxysteroid dehydrogenase activity by progesterone, medroxyprogesterone acetate, or danazol via openalex
The aetiology and pathogenesis of endometriosis via openalex
The genetic basis of endometriosis via openalex
The genetics of endometriosis via openalex
The Link between Exposure to Dioxin and Endometriosis: A Critical Reappraisal of Primate Data via openalex
The relation of endometriosis to menstrual characteristics, smoking, and exercise via openalex
The Relation of Endometriosis to Menstrual Characteristics, Smoking, and Exercise via openalex
The vascular endothelial growth factor (VEGF) +405G>C 5′-untranslated region polymorphism and increased risk of endometriosis in South Indian women: a case control study via openalex
Tumor necrosis factor alpha –C850T polymorphism is significantly associated with endometriosis in Asian Indian women via openalex
W2127850483 via openalex
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License: CC0 · commercial use OK

[1] Affected sib-pair analysis in endometriosis via openalex

[2] Allelic loss studies do not provide evidence for the “endometriosis-as-tumor” theory via openalex

[3] Allelotyping of endometriosis with adjacent ovarian carcinoma reveals evidence of a common lineage. via openalex

[4] Analysis of the codon 72 polymorphism of the TP53 gene in patients with endometriosis via openalex

[5] Androgen Receptor Gene Cytosine, Adenine, and Guanine Trinucleotide Repeats in Patients With Endometriosis via openalex

[6] Angiotensin I-converting enzyme ACE 2350*G and ACE-240*T-related genotypes and alleles are associated with higher susceptibility to endometriosis via openalex

[7] Association between human α 2-Heremans Schmidt glycoprotein (AHSG) polymorphism and endometriosis in Korean women via openalex

[8] Association of progesterone receptor gene polymorphism (PROGINS) with endometriosis, uterine fibroids and breast cancer via openalex

[9] Chronic Pelvic Pain via openalex

[10] Cytogenetic studies in endometriosis tissue via openalex

[11] DNA microarray analysis of gene expression profiles in deep endometriosis using laser capture microdissection via openalex

[12] Endometriosis and the development of malignant tumours of the pelvis. A review of literature via openalex

[13] Endometriosis is not associated with or linked to the GALT gene via openalex

[14] Endometriosis-Specific Genes Identified by Real-Time Reverse Transcription-Polymerase Chain Reaction Expression Profiling of Endometriosis Versus Autologous Uterine Endometrium via openalex

[15] EPIDEMIOLOGY OF ENDOMETRIOSIS via openalex

[16] ESHRE guideline for the diagnosis and treatment of endometriosis via openalex

[17] Estrogen receptor-alpha gene (T/C) Pvu II polymorphism in endometriosis and uterine fibroids. via openalex

[18] Estrogen receptor α dinucleotide repeat and cytochrome P450c17α gene polymorphisms are associated with susceptibility to endometriosis via openalex

[19] [Etiology and pathogenesis of endometriosis]. via openalex

[20] Expression of oestrogen receptor-alpha and -beta in ovarian endometriomata via openalex

[21] Genetic Alterations in Microsatellite Marker Sites among Tumor Suppressor Genes in Endometriosis via openalex

[22] Genetics of endometriosis: a role for the progesterone receptor gene polymorphism PROGINS? via openalex

[23] Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis. via openalex

[24] Genomewide Linkage Study in 1,176 Affected Sister Pair Families Identifies a Significant Susceptibility Locus for Endometriosis on Chromosome 10q26 via openalex

[25] Genomewide Linkage Study in 1,176 Affected Sister Pair Families Identifies a Significant Susceptibility Locus for Endometriosis on Chromosome 10q26 via openalex

[26] GSTM1, GSTT1 and CYP1A1 detoxification gene polymorphisms and their relationship with advanced stages of endometriosis in South Indian women via openalex

[27] Heritability and Molecular Genetic Studies of Endometriosis via openalex

[28] High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis via openalex

[29] Human endometriosis-derived permanent cell line (FbEM-1): establishment and characterization via openalex

[30] Increased prevalence of p53 overexpression from typical endometriosis to atypical endometriosis and ovarian cancer associated with endometriosis via openalex

[31] Increase in the number of integrinβ1-immunoreactive monocyte-lineage cells in experimentally-induced adenomyosis in mice via openalex

[32] Is There a Genetic Basis to Endometriosis? via openalex

[33] Lack of Association Between Endometriosis and N-acetyl transferase 1 (NAT1) and 2 (NAT2) Polymorphisms in a Japanese Population via openalex

[34] Lack of association between endometriosis and the<b><i>CYP17 Msp</i></b>A1 polymorphism in UK and Japanese populations via openalex

[35] Lack of association between endometriosis and the CYP17 MspA1 polymorphism in UK and Japanese populations. via openalex

[36] Linkage and association studies of the relationship between endometriosis and genes encoding the detoxification enzymes GSTM1, GSTT1 and CYP1A1 via openalex

[37] Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci. via openalex

[38] Microsatellite DNA assays reveal an allelic imbalance in p16Ink4, GALT, p53, and APOA2 loci in patients with endometriosis via openalex

[39] Molecular mechanisms and biological plausibility underlying the malignant transformation of endometriosis: a critical analysis via openalex

[40] Molecular Pathogenesis of Endometriosis; Toll-Like Receptor-4 A896G (D299G) Polymorphism: A Novel Explanation via openalex

[41] No Association of Endometriosis With Glutathione S-Transferase M1 and T1 Null Mutations in a Japanese Population via openalex

[42] Polymorphic (CAG)n repeats in the androgen receptor gene via openalex

[43] Polymorphism for Transforming Growth Factor Beta 1-509 (TGF-B1-509): Association with Endometriosis via openalex

[44] Polymorphisms in the estrogen receptor β gene but not estrogen receptor α gene affect the risk of developing endometriosis in a Japanese population via openalex

[45] Polymorphisms in the promoter regions of FAS and FASL genes as candidate genetic factors conferring susceptibility to endometriosis via openalex

[46] Preliminary molecular genetic analysis of the Receptor Interacting Protein 140 (RIP140) in women affected by endometriosis via openalex

[47] Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis via openalex

[48] Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis1 via openalex

[49] PROGINS receptor gene polymorphism is associated with endometriosis via openalex

[50] [Relationship between endometriosis and glutathione S-transferase M1, T1 genes of the Uygurs and Hans in Xinjiang]. via openalex

[51] Role of shigella infection in endometriosis: A novel hypothesis via openalex

[52] Steroidal regulation of endometriosis tissue: lack of induction of 17β-hydroxysteroid dehydrogenase activity by progesterone, medroxyprogesterone acetate, or danazol via openalex

[53] The aetiology and pathogenesis of endometriosis via openalex

[54] The genetic basis of endometriosis via openalex

[55] The genetics of endometriosis via openalex

[56] The Link between Exposure to Dioxin and Endometriosis: A Critical Reappraisal of Primate Data via openalex

[57] The relation of endometriosis to menstrual characteristics, smoking, and exercise via openalex

[58] The Relation of Endometriosis to Menstrual Characteristics, Smoking, and Exercise via openalex

[59] The vascular endothelial growth factor (VEGF) +405G>C 5′-untranslated region polymorphism and increased risk of endometriosis in South Indian women: a case control study via openalex

[60] Tumor necrosis factor alpha –C850T polymorphism is significantly associated with endometriosis in Asian Indian women via openalex

[61] W2127850483 via openalex

[62] W2128319359 via openalex

[63] W2141343893 via openalex

[64] W2045487737 via openalex

[65] W2142928349 via openalex

[66] W2040475011 via openalex

[67] W2150172738 via openalex

[68] W2155026799 via openalex

[69] W2025204070 via openalex

[70] W2162285258 via openalex

[71] W2007940587 via openalex

[72] W2168412098 via openalex

[73] W1964266840 via openalex

[74] W1905194783 via openalex

[75] W1636567173 via openalex

[76] W2737090464 via openalex

[77] W1605937978 via openalex

[78] W4237209429 via openalex

[79] W4237269866 via openalex

[80] W1586171642 via openalex

[81] W4285719527 via openalex

[82] W6638534860 via openalex

[83] W6648390844 via openalex

[84] W6668888355 via openalex

[85] W6671125951 via openalex

[86] W6678861672 via openalex

[87] W6819229435 via openalex

[88] W2105981541 via openalex

[89] W1511789414 via openalex

[90] W2102562347 via openalex

[91] W2095613768 via openalex

[92] W2092513068 via openalex

[93] W206153150 via openalex

[94] W2119408787 via openalex

[95] W2053309322 via openalex

[96] W2127368795 via openalex

[97] W2127539255 via openalex