Affected sib-pair analysis in endometriosis
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⤵ 38 in-corpus citations
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This paper reviews genetic evidence for endometriosis and outlines the affected-sib pair analysis approach used in the OXEGENE study to identify disease susceptibility genes.
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Abstract
This paper (i) reviews the current clinical and molecular genetic data which strongly suggest that endometriosis has a genetic basis; (ii) outlines the general principles of affected-sib pair analysis; and (iii) describes the Oxford Endometriosis Gene (OXEGENE) Study which aims, using a positional cloning approach, to identify susceptibility genes involved in the development of the disease.
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Cited by (38)
- The quest for genetic sequence variants conferring risk of endometriosis 2020
- Differentially expressed genes: OCT-4, SOX2, STAT3, CDH1 and CDH2, in cultured mesenchymal stem cells challenged with serum of women with endometriosis 2017
- Endometriosis, Cytological Findings 2017
- Evaluation of Risk Factors Associated with Endometriosis in Infertile Women. 2016
- Tumor Necrosis Factor and Interleukin‐6 Gene Polymorphisms and Endometriosis Risk in Asians: A Systematic Review and Meta‐Analysis 2013
- Replication of endometriosis-associated single-nucleotide polymorphisms from genome-wide association studies in a Caucasian population 2013
- Reproductive prognosis in daughters of women with and without endometriosis 2013
- Association of endometriosis risk and genetic polymorphisms involving biosynthesis of sex steroids and their receptors: an updating meta-analysis 2012
- Endometriosis 2012
- Pathogenesis of endometriosis: the role of genetics, inflammation and oxidative stress 2012
- Genetic Polymorphisms and Molecular Pathogenesis of Endometriosis 2012
- Pathophysiological factors and genetic association in endometriosis 2011
- Ovarian cancer-associated polymorphisms in the BNC2 gene among women with endometriosis 2011
- Genetic variation in the sex hormone metabolic pathway and endometriosis risk: an evaluation of candidate genes 2011
- Differential Expression of MicroRNAs between Eutopic and Ectopic Endometrium in Ovarian Endometriosis 2010
- Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1 2010
- Rectovaginal septum endometriosis: an immunohistochemical analysis of 62 cases. 2009
- Endometriosis 2008
- Endometriosis: Pathogenesis, diagnosis, therapy and association with cancer (Review) 2008
- ORIGINAL ARTICLE: Tumor Necrosis Factor (TNF)–TNF Receptor Gene Polymorphisms and Their Serum Levels in Korean Women with Endometriosis 2008
- Functional genetic polymorphisms and female reproductive disorders: Part II--endometriosis 2008
- Why Do They Do It? 2007
- Differences in characteristics among 1,000 women with endometriosis based on extent of disease 2007
- Quantitative DNA perturbations of p53 in endometriosis: analysis of American and Icelandic cases 2005
- Lack of association between endometriosis and the<b><i>CYP17 Msp</i></b>A1 polymorphism in UK and Japanese populations 2005
- Endometriosis: New Genetic Approaches and Therapy 2005
- Where Are the Genes That Cause Endometriosis? 2005
- The tumor necrosis factor-α promoter −1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population 2004
- Association between human α 2-Heremans Schmidt glycoprotein (AHSG) polymorphism and endometriosis in Korean women 2004
- Genetic Basis of Endometriosis 2004
- Serum and endometrial markers 2004
- Endometriosis 2004
- Genetics of endometriosis 2003
- Heritability and candidate genes for endometriosis 2003
- Genetics of Endometriosis 2003
- High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis 2002
- Molecular approach to common causes of female infertility 2002
- The Genetic Epidemiology of Spontaneous Endometriosis in the Rhesus Monkey 2002
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- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:13:19.284922+00:00
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