Is There a Genetic Basis to Endometriosis?
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⤵ 31 in-corpus citations
Abstract
It is likely that endometriosis is a common multifactorial disease, like diabetes and asthma, caused by an interaction between multiple gene loci and the environment. Such conditions do not have a clear Mendelian pattern of inheritance. This chapter reviews the existing evidence, in human and non-human primates, that suggests there is a genetic basis to endometriosis. The environmental agents that have been implicated in the development of endometriosis are also reviewed. The identification of genetic loci conferring susceptibility to endometriosis using linkage analysis may lead to a better understanding of disease aetiology and, in time, improved therapeutic strategies and diagnostic methods.
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Cited by (31)
- [Analysis of the factors contributing to endometriosis in China and UK]. 2022
- The bimodal role of matrix metalloproteinases and their inhibitors in etiology and pathogenesis of endometriosis (Review) 2018
- Association between glutathione S-transferase M1/T1 gene polymorphisms and susceptibility to endometriosis: A systematic review and meta-analysis 2016
- Glutathione S-transferase M1 polymorphism and endometriosis susceptibility: A meta-analysis 2014
- Pathological Aspects of Endometriosis 2012
- Genetic Polymorphisms and Molecular Pathogenesis of Endometriosis 2012
- Genetic variation in the sex hormone metabolic pathway and endometriosis risk: an evaluation of candidate genes 2011
- Advances in the genetics of endometriosis 2010
- Endometriosis 2009
- Patientinnenzentrierte Aspekte der Endometriose 2008
- Endometriosis and Genetic Polymorphisms 2007
- MOTS CLES : Endométriose - Sténose urétérale - Diagnostic précoce - Hormonothérapie Technique Chirurgicale - Surveillance 2006
- Measuring quality of life in women with endometriosis: tests of data quality, score reliability, response rate and scaling assumptions of the Endometriosis Health Profile Questionnaire 2006
- Eziopatogenesi dell'endometriosi 2005
- The function of the SNP in the MMP1 and MMP3 promoter in susceptibility to endometriosis in China 2005
- No Association of Endometriosis With Glutathione S-Transferase M1 and T1 Null Mutations in a Japanese Population 2004
- Development of the Short Form Endometriosis Health Profile Questionnaire: The EHP-5 2004
- The tumor necrosis factor-α promoter −1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population 2004
- Analysis of the involvement of CCR5- 32 and CCR2-V64I variants in the development of endometriosis 2004
- Genetics of Endometriosis 2003
- Association study of genetic polymorphisms in endometriosis 2003
- Subfertility: causes, treatment and outcome 2003
- Patientinnenzentrierte Aspekte der Endometriose 2003
- Linkage and association studies of the relationship between endometriosis and genes encoding the detoxification enzymes GSTM1, GSTT1 and CYP1A1 2001
- Association between endometriosis and N-acetyl transferase 2 polymorphisms in a UK population 2001
- Redefining endometriosis: Endometriosis is an entity with extreme pleiomorphism 2000
- Aetiology and medical treatment of endometriosis 2000
- Die Archimetra als neues morphologisch-funktionelles Konzept des Uterus sowie als Ort der Primärerkrankung bei Endometriose 1999
- Absence of a relationship between endometriosis and the N314D polymorphism of galactose-1-phosphate uridyl transferase in a UK population 1999
- Endometriosis: a dysfunction and disease of the archimetra 1998
- Excessive angiogenesis: a new theory for endometriosis 1998
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