Analysis of factors affecting pregnancy outcomes in patients with adenomyosis after high intensity focused ultrasound ablation: a retrospective study
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This retrospective study found that high intensity focused ultrasound (HIFU) may improve fertility in adenomyosis patients, though pelvic adhesion, prior infertility, and lesion volume negatively impact pregnancy, while IVF-ET after GnRHa treatment improves conception rates.
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Abstract
OBJECTIVES: To investigate all pregnancies and analyze the factors influencing pregnancy outcomes in patients with adenomyosis after high intensity focused ultrasound (HIFU). MATERIALS AND METHODS: A total of 231 patients with adenomyosis who completed HIFU and wished to conceive were enrolled. The symptom improvement and information of pregnancy were recorded during the follow-up period. Factors influencing pregnancy outcomes were analyzed using multivariate regression analysis and survival analysis. RESULTS: < 0.05). CONCLUSIONS: HIFU seems to have a beneficial effect on fertility of patients with adenomyosis. Pelvic adhesion, infertility history, and large adenomyotic lesion volume have adverse effects on pregnancy, but IVF-ET following GnRHa after HIFU could increase the pregnancy chance.
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Cited by (5)
- Adenomyosis and fertility: from pathophysiology to optimizing reproductive outcomes 2026
- Treatment strategies for adenomyosis before and after introducing USgHIFU in Shenzhen 2025
- Effect of pelvic adhesions on reproductive outcomes following high‐intensity focused ultrasound in patients with adenomyosis 2025
- Updates on adenomyosis and fertility 2025
- Pregnancy outcomes and influencing factors following high-intensity focused ultrasound treatment for adenomyosis: a single-center retrospective study 2025
Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-06-02T00:32:39.140588+00:00
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