Unusual Case of Postmenopausal Diffuse Endometriosis Mimicking Metastastic Ovarian Malignancy

Case report OA: closed CC0 ⤵ 12 in-corpus citations
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This case report describes diffuse peritoneal endometriosis and ovarian endometriomas in a postmenopausal woman mimicking metastatic ovarian cancer on FDG PET/CT.

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Abstract

Endometriosis is a common gynecologic condition of the premenopausal years. However, postmenopausal endometriosis is rare (2.2%) and thought to be related to high level of circulating estrogen, especially in hormonal replacement therapy. We present a case of a 69-year-old postmenopausal woman, previously healthy and on no regular medication, with diffuse peritoneal endometriosis and bilateral ovarian endometrioma mimicking metastatic ovarian carcinoma on FDG PET/CT. Both ovarian endometrioma had low-grade activity, but more strikingly, there was diffuse FDG-avid peritoneal dissemination and gross ascites. Endometriosis should not be totally disregarded as a differential diagnosis even at postmenopausal status.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Multimodal Imaging Multimodal Imaging Neoplasms, Glandular and Epithelial Ovarian Neoplasms Positron-Emission Tomography Positron-Emission Tomography Tomography, X-Ray Computed Tomography, X-Ray Computed Aged Aged Carcinoma, Ovarian Epithelial Carcinoma, Ovarian Epithelial Diagnosis, Differential Diagnosis, Differential Endometriosis Endometriosis Female Female Fluorodeoxyglucose F18

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (9)

Cited by (12)

Source provenance

europepmc
last seen: 2026-11-11T06:12:07.612938+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:16:31.290043+00:00
License: CC0 · commercial use OK