Unusual Case of Postmenopausal Diffuse Endometriosis Mimicking Metastastic Ovarian Malignancy

Case report OA: closed CC0 ⤵ 12 in-corpus citations
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This case report describes diffuse peritoneal endometriosis and ovarian endometriomas in a postmenopausal woman mimicking metastatic ovarian cancer on FDG PET/CT.

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Abstract

Endometriosis is a common gynecologic condition of the premenopausal years. However, postmenopausal endometriosis is rare (2.2%) and thought to be related to high level of circulating estrogen, especially in hormonal replacement therapy. We present a case of a 69-year-old postmenopausal woman, previously healthy and on no regular medication, with diffuse peritoneal endometriosis and bilateral ovarian endometrioma mimicking metastatic ovarian carcinoma on FDG PET/CT. Both ovarian endometrioma had low-grade activity, but more strikingly, there was diffuse FDG-avid peritoneal dissemination and gross ascites. Endometriosis should not be totally disregarded as a differential diagnosis even at postmenopausal status.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Multimodal Imaging Multimodal Imaging Neoplasms, Glandular and Epithelial Ovarian Neoplasms Positron-Emission Tomography Positron-Emission Tomography Tomography, X-Ray Computed Tomography, X-Ray Computed Aged Aged Carcinoma, Ovarian Epithelial Carcinoma, Ovarian Epithelial Diagnosis, Differential Diagnosis, Differential Endometriosis Endometriosis Female Female Fluorodeoxyglucose F18

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (9)

Cited by (12)

Source provenance

europepmc
last seen: 2026-10-12T06:17:10.165071+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:16:31.290043+00:00
License: CC0 · commercial use OK