Unusual Case of Postmenopausal Diffuse Endometriosis Mimicking Metastastic Ovarian Malignancy

Rajani Agarwal Sharma, Elaine Yuen Phin Lee, Elaine Lee, Varut Vardhanabhuti, Pek‐Lan Khong, Pek-Lan Khong, Siew-Fei Ngu, Siew‐Fei Ngu
Clinical nuclear medicine · 2015 · vol. 41(2) , pp. e120–e122 · doi:10.1097/rlu.0000000000001038 · PMID:26462045 · W2464403656
article OA: closed CC0 ⤵ 12 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report describes diffuse peritoneal endometriosis and ovarian endometriomas in a postmenopausal woman mimicking metastatic ovarian cancer on FDG PET/CT.

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Abstract

Endometriosis is a common gynecologic condition of the premenopausal years. However, postmenopausal endometriosis is rare (2.2%) and thought to be related to high level of circulating estrogen, especially in hormonal replacement therapy. We present a case of a 69-year-old postmenopausal woman, previously healthy and on no regular medication, with diffuse peritoneal endometriosis and bilateral ovarian endometrioma mimicking metastatic ovarian carcinoma on FDG PET/CT. Both ovarian endometrioma had low-grade activity, but more strikingly, there was diffuse FDG-avid peritoneal dissemination and gross ascites. Endometriosis should not be totally disregarded as a differential diagnosis even at postmenopausal status.

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Condition tags

mesh:D004715endometriosisendometrioma

MeSH descriptors

Endometriosis Multimodal Imaging Neoplasms, Glandular and Epithelial Ovarian Neoplasms Positron-Emission Tomography Tomography, X-Ray Computed Aged Carcinoma, Ovarian Epithelial Diagnosis, Differential Endometriosis Female Fluorodeoxyglucose F18 Humans Neoplasm Metastasis Neoplasms, Glandular and Epithelial Neoplasms, Glandular and Epithelial Ovarian Neoplasms Ovarian Neoplasms Postmenopause Radiopharmaceuticals

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (9)

Cited by (12)

Source provenance

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License: CC0 · commercial use OK