Pathological Aspects of Endometriosis

Agatha Kondi-Pafitis
In: Endometriosis - Basic Concepts and Current Research Trends · 2012 · doi:10.5772/32433 · W1539435549
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This paper explores how the disease's extent, local biochemical factors, and activated mast cells contribute to endometriosis symptoms, and notes that ruptured ovarian endometriomas can mimic malignancy.

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This chapter provides a comprehensive review of the pathological features associated with endometriosis, detailing the histological characteristics and molecular mechanisms underlying the disease. It examines the presence of ectopic endometrial-like tissue outside the uterus, highlighting the inflammatory response, angiogenesis, and hormonal dependencies that drive lesion formation and progression. The text also discusses the variability in pathological presentation across different stages of the disease and the challenges in diagnosing deep infiltrating forms based on histology alone. This paper is centrally about endometriosis — specifically focusing on the pathological aspects and histological diagnosis of the condition.

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Abstract

actual extend of the disease and the various local biochemical factors and the local action of activated mast cells may be responsible for this symptom. In rare cases with ovarian endometriosis, acute abdomen because of rupture of ovarian cystic masses and ascites raise the suspicion of malignancy
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Open access Submitted: 11 April 2011 Published: 09 May 2012 DOI: 10.5772/32433 From the Edited Volume Edited by Koel Chaudhury and Baidyanath Chakravarty Submitted: 11 April 2011 Published: 09 May 2012 © 2012 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Discover 2026 Nobel Laureate Francis Halzen’s chapter on IntechOpen >

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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