Kinderwunschtherapie mit Spendersamen – auf welcher Basis entscheiden wir über Umfang und Konsequenzen der vorausgehenden Diagnostik?

In: Gynäkologische Endokrinologie · 2023 · vol. 21(2) , pp. 146–150 · doi:10.1007/s10304-023-00503-8 · W4328129325
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AI-generated summary by claude@2026-06+body, 2026-06-08

This literature review analyzes studies on diagnostics and treatment decisions for donor sperm therapy, focusing on endometriosis, uterine fibroids, and assisted reproduction outcomes.

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The paper discusses how decisions are made regarding the scope and consequences of pre-treatment diagnostics in fertility therapy using donor sperm, focusing on what evidence and guidelines are used to justify diagnostic steps before assisted reproduction. It is not an original clinical study, and it explicitly centers on interpretation of recommendations rather than presenting new patient outcomes, with the limitation that it relies on cited literature and guideline frameworks. A key point is that the breadth of diagnostic workups and their impact on clinical decision-making must be grounded in appropriate standards, but the practical basis for determining that scope is complex. Relevance to endometriosis: endometriosis is referenced through the inclusion of related fertility and infertility literature in the provided source list and contextual guideline landscape, though the paper’s main focus is donor-sperm fertility diagnostics rather than endometriosis itself.

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Literatur Adamson GD, Pasta DJ (2010) Endometriosis fertility index: the new, validated endometriosis staging system. Fertil Steril 94(5):1609–1615 Alborzi S, Zahiri Sorouri Z, Askari E, Poordast T, Chamanara K (2019) The success of various endometrioma treatments in infertility: a systematic review and meta-analysis of prospective-studies. Reprod Med Biol 18:312–322 Allen CP, Marconi N, McLernon DJ, Bhattacharya S, Maheshwari A (2021) Outcomes of pregnancies using donor sperm compared with those using partner sperm: systematic review and meta-analysis. Hum Reprod Update 27(1):190–211. https://doi.org/10.1093/humupd/dmaa030 AWMF-Leitlinie. „Diagnostik und Therapie vor einer assistierten reproduktionsmedizinischen Behandlung.“ 2019. Bafort C, Beebeejaun Y, Tomassetti C, Bosteels J, Duffy JMN (2020) Laparoscopic surgery for endometriosis. Cochrane Database Syst Rev Barnitzky S, Blumenauer V, Czeromin U, Fehr D, Grewe C, Krüssel JS, Kupka MS, Tandler-Schneider A, Tauchert S (2022) DIR annual 2021—the German IVF register. J Reproduktionsmed Endokrinol 19(5):241–294 Bortoletto P, Willson S, Romanski PA, Davis OK, Rosenwaks Z (2021) Reproductive outcomes of women aged 40 and older undergoing IVF with donor sperm. Hum Reprod 36(1):229–235 Diego D, Medline A, Shandley LM, Kawwass JF, Hipp HS (2022) Donor sperm recipients: fertility treatments, trends, and pregnancy outcomes. J Assist Reprod Genet 39(10):2303–2310 Dolmans MM, Isaacson K, Zhang W, Gordts S, Munro MG, Stewart EA, Bourdon M, Santulli P, Donnez J (2021) Intramural myomas more than 3‑4 centimeters should be surgically removed before in vitro fertilization. Fertil Steril 116(4):945–958 Eisenberg VH, Weil C, Chodick G, Shalev V (2018) Epidemology of endometriosis: a large population based database study from a healthcare provider with 2 million members. BJOG 125(1):55–62 ESHRE, Endometriosis Guideline Development Group. “Guideline of European Society of Human Reproduction and Embryology: Endometriosis.” 2022. Freytag D, Günther V, Maass N, Alkatout I (2021) Uterine fibroids and infertility. Diagnostics 11:1455 Harb HM, Gallos ID, Chu J, Harb M, Coomarasamy A (2013) The effect of endometriosis on in vitro fertilisation outcome: a systematic review and meta-analysis. BJOG 120(11):1308–1320 (2019) 1. HFEA. Trends in egg and sperm donation. https://www.hfea.gov.uk/media/2808/trends-in-egg-and-sperm-donation-final.pdf. Zugegriffen: 15.11.2022 Linara-Demakakou E, Bodri D, Wang J, Arian-Schad M, Macklon N, Ahuja K (2020) Cumulative live birth rates following insemination with donor spermatozoa in single women, same-sex couples and heterosexual patients. Reprod Biomed Online 41(6):1007–1010 Practice Committee of the American Society for Reproductive Medicine (2021) Fertility evaluation of infertile women: a committee opinion. Fertil Steril 116(5):1255–1265 Practice Committee of the American Society for Reproductive Medicine (2017) Removal of myomas in asymptomatic patients to improve fertility and/ or reduce miscarriage rate: a guideline. Fertil Steril 108:416–425 Munro MG, Critchley HO, Broder MS, Fraser IS (2011) FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. Int J Gynaecol Obstet 113(1):3–13 Payson M, Leppert P, Segars J (2006) Epidemiology of myomas. Obstet Gynecol Clin North Am 33(1):1–11 Pennings G (2017) Disclosure of donor conception, age of disclosure and the well-being of donor offspring. Hum Reprod 32:969–973 Pohjonen EM, Söderström-Anttila V, Bergh C, Loft A, Magnusson Å, Pinborg A, Oldereid NB, Petzold M, Romundstad LB, Laivuori H (2022) Obstetric and perinatal risks after the use of donor sperm: a systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol 274:210–228 Raja NS, Russell CB, Moravek MB (2022) Assisted reproductive technology: considerations for the nonheterosexual population and single parents. Fertil Steril 118(1):47–53. https://doi.org/10.1016/j.fertnstert.2022.04.012 Tur-Kaspa I, Gal M, Hartman M, Hartman J, Hartman A (2006) A prospective evaluation of uterine abnormalities by saline infusion sonohysterography in 1,009 women with infertility or abnormal bleeding. Fertil Steril 86:1731–1735 Uyanik E, Erden M, Tez CR, Zaim OC, Polat M, Mumusoglu S, Yarali H (2022) The effect of the presence of intramural myomas smaller than 6 cm on reproductive outcome in IVF treatment: a systematic review and meta-analysis. Hum Reprod 37; Suppl 1: deac106.039 Author information Authors and Affiliations Corresponding author Ethics declarations Interessenkonflikt C. Sondermann und B. Sonntag geben an, dass kein Interessenkonflikt besteht. Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. Additional information Redaktion Ricardo Felberbaum, Kempten Maren Goeckenjan, Dresden Barbara Sonntag, Hamburg QR-Code scannen & Beitrag online lesen Rights and permissions About this article Cite this article Sondermann, C., Sonntag, B. Kinderwunschtherapie mit Spendersamen – auf welcher Basis entscheiden wir über Umfang und Konsequenzen der vorausgehenden Diagnostik?. Gynäkologische Endokrinologie 21, 146–150 (2023). https://doi.org/10.1007/s10304-023-00503-8 Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s10304-023-00503-8

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