Decoding the multifactorial etiology of chronic endometritis

Gene Jiing‐Yun You, Guanying You, Shuyi Yu, Meng Liu, Lianghui Diao, Ruochun Lian, Yuye Li
Placenta · 2025 · vol. 180 , pp. 118–127 · doi:10.1016/j.placenta.2025.09.007 · PMID:40957733 · W4414105629
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This paper investigates the complex factors contributing to the development of chronic endometritis.

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Abstract

Chronic endometritis (CE) is a persistent inflammatory disorder of the endometrium, typically marked by abnormal plasma cell infiltration. It is closely associated with adverse pregnancy outcomes. The pathogenesis of CE involves a complex interplay of both infectious and non-infectious factors. Infectious etiologies include ascending infection pathways, pelvic infection pathways, sexually transmission, hematogenous infection pathways and special infections, while non-infectious factors encompass uterine structural pathology, autoimmune disorders and iatrogenic factors. Considering the multifactorial etiology of CE, adopting a personalized management approach that integrates both microbial and immune factors may enhance pregnancy outcomes for CE women.

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Condition tags

disambig:endometritis

MeSH descriptors

Endometritis Endometritis Endometritis Chronic Disease Female Humans Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
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License: CC0 · commercial use OK