In brief: Chronic endometritis (CE) impairs endometrial receptivity via unknown mechanisms. This study reveals that suppression of the C/EBPδ-sphingosine kinase 1 (SphK1)-sphingosine-1-phosphate (S1P) axis in CE leads to decidualization def…
Adenomyosis, characterized by the invasion of endometrial cells into the myometrium, may disrupt immune homeostasis within the eutopic endometrium, thereby impairing endometrial receptivity. This retrospective case-control study aimed to in…
BACKGROUND: Chronic endometritis (CE) is a persistent inflammatory condition associated with adverse pregnancy outcomes. Although impaired endometrial angiogenesis is thought to contribute to its pathogenesis, the underlying molecular mecha…
Chronic endometritis (CE) is a persistent inflammatory disorder of the endometrium, typically marked by abnormal plasma cell infiltration. It is closely associated with adverse pregnancy outcomes. The pathogenesis of CE involves a complex i…
OBJECTIVE: This study was conducted to determine the influence of the number of CD138+ cells in the proliferative endometrium on pregnancy outcomes. METHODS: This retrospective cohort study was conducted from January to August 2018. A tota…