OBJECTIVE: There is currently no consensus on the risk factors for recurrent ovarian endometrioma after surgery. This study aimed to identify independent risk factors and develop a clinical nomogram to predict postoperative recurrence. MET…
OBJECTIVE: To develop and compare a random survival forest (RSF) model and a Cox regression model-for predicting postoperative recurrence in patients with ovarian endometrioma. METHODS: The primary outcomes of the study were the recurrence…
BACKGROUND: Although azithromycin has demonstrated potential therapeutic efficacy in the treatment of chronic endometritis (CE), comprehensive studies on the optimal timing of administration are lacking. Our study aims to evaluate the impac…
OBJECTIVE: To explore the regulatory function and mechanism of CXCL14 in endometriosis. METHODS: Quantitative real-time polymerase chain reaction (qRT-PCR) was used to examine the expression of CXCL14 in eutopic and ectopic endometrial str…
Chronic endometritis (CE) is a persistent inflammatory disorder of the endometrium, typically marked by abnormal plasma cell infiltration. It is closely associated with adverse pregnancy outcomes. The pathogenesis of CE involves a complex i…
Ovarian clear cell carcinoma (OCCC) represents a rare and aggressive subtype of epithelial ovarian cancer with distinctive clinical and molecular characteristics. However, the identification, origin, and molecular features of the malignant …
BACKGROUND: Adenomyosis is a uterine disorder closely linked to infertility and adverse pregnancy outcomes. Despite its clinical significance, the mechanisms by which adenomyosis impairs embryo implantation and perinatal outcomes remain inc…
OBJECTIVE: This study aims to construct a knowledge map of polycystic ovary syndrome (PCOS)-cancer research through bibliometric analysis to elucidate its developmental trajectory and global research landscape, and further employ bioinforma…
BACKGROUND: Chronic endometritis (CE) has been widely recognized as a potential cause of infertility, however, access to effective treatment is a formidable challenge due to the rudimentary understanding of the pathogenesis of persistent CE…
OBJECTIVE: Endometriosis increases ovarian cancer (OC) risk through genetic mutations, chronic inflammation, and hormonal dysregulation, yet the underlying molecular pathways remain underexplored. This study aims to identify endometriosis-a…
Female infertility represents a significant global medical concern, attributable to a spectrum of disorders affecting the reproductive system, which encompasses premature ovarian insufficiency (POI), polycystic ovary syndrome (PCOS), Asherm…
OBJECTIVE: To investigate whether the 115T/C, 240A/G and 1531C/T polymorphisms of CYP19 gene are associated with the risk of moderate/severe endometriosis. METHODS: Polymerase chain reaction-restriction fragment length polymorphism (PCR-RF…