The #Enzian classification: A comprehensive non‐invasive and surgical description system for endometriosis

J. Keckstein, Ertan Saridogan, Ertan Sarıdoğan, U. Ulrich, Uwe A Ulrich, Martin Sillem, Peter Oppelt, Karl-Werner Schweppe, Karl W Schweppe, Harald Krentel, Elisabeth Janschek, C. Exacoustós, Caterina Exacoustos, Mario Malzoni, Michael Mueller, Michael D. Mueller, Horace Roman, George Condous, G. Condous, Axel Forman, Frank W Jansen, Attila Bokor, Voicu Simedrea, Gernot Hudelist
Acta obstetricia et gynecologica Scandinavica · 2021 · vol. 100(7) , pp. 1165–1175 · doi:10.1111/aogs.14099 · PMID:33483970 · W3123449121
article OA: hybrid CC0 ⤵ 206 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

The #Enzian classification is a new, comprehensive system developed through consensus for describing endometriosis non-invasively and surgically, encompassing peritoneal, ovarian, and deep disease, along with adhesions and organ involvement.

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Abstract

Advances in preoperative diagnostics as well as in surgical techniques for the treatment of endometriosis, especially for deep endometriosis, call for a classification system, that includes all aspects of the disease such as peritoneal endometriosis, ovarian endometriosis, deep endometriosis, and secondary adhesions. The widely accepted revised American Society for Reproductive Medicine classification (rASRM) has certain limitations because of its incomplete description of deep endometriosis. In contrast, the Enzian classification, which has been implemented in the last decade, has proved to be the most suitable tool for staging deep endometriosis, but does not include peritoneal or ovarian disease or adhesions. To overcome these limitations, a comprehensive classification system for complete mapping of endometriosis, including anatomical location, size of the lesions, adhesions and degree of involvement of the adjacent organs, that can be used with both diagnostic and surgical methods, has been created through a consensus process and will be described in detail-the #Enzian classification.

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Outcome instruments

rASRM Enzian

Condition tags

mesh:D004715endometriosis

MeSH descriptors

Consensus Endometriosis Severity of Illness Index Symptom Assessment Databases, Factual Endometriosis Endometriosis Endometriosis Female Humans Societies, Medical Symptom Assessment

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (25)

Cited by (50)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
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License: CC0 · commercial use OK