Primary umbilical endometriosis: a case report and review of literature

Anuradha Ghosh, Sachchidananda Das
Archives of gynecology and obstetrics · 2014 · vol. 290(4) , pp. 807–809 · doi:10.1007/s00404-014-3291-8 · PMID:24930115 · W1974545797
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This case report and literature review examines primary umbilical endometriosis, a rare variant of extragenital endometriosis presenting at the navel.

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This paper reports a case of primary umbilical endometriosis and provides a review of the relevant medical literature. The authors describe the clinical presentation and diagnostic work-up at a high level and synthesize prior reports on umbilical (extragenital) endometriosis, with discussion of management options. A key caveat is that, as a case report with literature review, it cannot establish causal mechanisms or the effectiveness of any specific approach beyond what has been reported in the literature. This paper is centrally about endometriosis — specifically primary umbilical endometriosis presenting as an extragenital lesion.

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References Spaziani E, Picchio M, Di Filippo A, De Cristofano C, Ceci F, Stagnitti F (2009) Spontaneous umbilical endometriosis: a case report with one-year follow-up. Clin Exp Obstet Gynecol 36:263–264 Rosina P, Pugliarello S, Colato C, Girolomoni G (2008) Endometriosis of umbilical cicatrix: case report and review of the literature. Acta Dermatovenerol Croat 16:218–221 Markham SM, Carpenter SE, Rock JA (1989) Extrapelvic endometriosis. Obstet Gynecol Clin North Am 16:193–219 Fancellu A, Pinna A, Manca A, Capobianco G, Porcu A (2013) Primary umbilical endometriosis. Case report and discussion on management options. Int J Surg Case Rep 4(12):1145–1148 Goldberg JM, Bedaiwy MA (2007) Recurrent umbilical endometriosis after laparoscopic treatment of minimal pelvic endometriosis: a case report. J Reprod Med 52(6):551–552 Michowitz M, Baratz M, Stavorovsky M (1983) Endometriosis of the umbilicus. Dermatologica 167(6):326–330 Bagade PV, Guirguis MM (2009) Menstruating from the umbilicus as a rare case of primary umbilical endometriosis: a case report. J Med Case Rep 10(3):9326 Chatzikokkinou P, Thorfinn J, Angelidis IK, Papa G, Trevisan G (2009) Spontaneous endometriosis in an umbilical skin lesion. Acta Dermatovenerol Alp Panonica Adriat 18(3):126–130 Dessy LA, Buccheri EM, Chiummariello S, Gagliardi DN, Onesti MG (2008) Umbilical endometriosis, our experience. In Vivo 22(6):811–815 Liu DT, Hitchcock A (1986) Endometriosis: its association with retrograde menstruation, dysmenorrhoea and tubal pathology. Br J Obstet Gynaecol 93:859–862 Mechsner S, Bartley J, Infanger M, Loddenkemper C, Herbel J, Ebert AD (2009) Clinical management and immunohistochemical analysis of umbilical endometriosis. Arch Gynecol Obstet 280(2):235–242 Victory R, Diamond MP, Johns DA (2007) Villar’s nodule: a case report and systematic literature review of endometriosis externa of the umbilicus. J Minim Invasive Gynecol 14(1):23–32 Kyamidis K, Lora V, Kanitakis J (2011) Spontaneous cutaneous umbilical endometriosis: report of a new case with immunohistochemical study and literature review. Dermatol Online J 17(7):5 Yu CY, Perez-Reyes M, Brown JJ, Borrello JA (1994) MR appearance of umbilical endometriosis. J Comput Assist Tomogr 18(2):269–271 Latcher JW (1953) Endometriosis of the umbilicus. Am J Obstet Gynecol 66(1):161–168 Khaled A, Hammami H, Fazaa B, Zermani R, Ben Jilani S, Kamoun MR (2008) Primary umbilical endometriosis: a rare variant of extragenital endometriosis. Pathologica 100(6):473–475 Obata K, Ikoma N, Oomura G, Inoue Y (2013) Clear cell adenocarcinoma arising from umbilical endometriosis. J Obstet Gynaecol Res 39:455–461 Elm MK, Twede JV, Turiansky GW (2008) Primary cutaneous endometriosis of the umbilicus: a case report. Cutis 81:124–126 Conflict of interest None. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Ghosh, A., Das, S. Primary umbilical endometriosis: a case report and review of literature. Arch Gynecol Obstet 290, 807–809 (2014). https://doi.org/10.1007/s00404-014-3291-8 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-014-3291-8

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Endometriosis Umbilicus Adult Endometriosis Female Humans Menstrual Cycle Umbilicus

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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