The Impact of Endometriosis on Pregnancy

Panagiotis Tsikouras, Efthymios Oikonomou, Anastasia Bothou, Αnastasia Bothou, Penelopi Chaitidou, Dimitrios Kyriakou, Konstantinos Nikolettos, Sotirios Andreou, F Gaitatzi, Foteini Gaitatzi, Theopi Nalbanti, Panagiotis Peitsidis, Spyridon Michalopoulos, Stefanos Zervoudis, Georgios Iatrakis, Nikolaos Nikolettos
Journal of personalized medicine · 2024 · vol. 14(1) , pp. 126 · doi:10.3390/jpm14010126 · PMID:38276248 · W4391098597
review OA: gold CC0 ⤵ 10 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Endometriosis negatively impacts natural and assisted conception, leads to increased obstetrical complications, and necessitates further research into tailored pregnancy monitoring.

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Abstract

Despite the increased frequency of endometriosis, it remains one of the most enigmatic disorders regarding its effects on pregnancy. Endometriosis adversely affects both natural and assisted conception. Impaired folliculogenesis, which causes follicular dysfunction and low egg quality, as well as luteal phase problems, reduced fertilization, and abnormal embryogenesis, are some of the mechanisms advocated to explain reproductive dysfunction. There is a rising need for a comprehensive study of the potential negative consequences of this condition on pregnancy outcomes, including the postpartum period, as more women with a medical history of endometriosis become pregnant. Obstetrical complications (small for gestational age [SGA], cesarean section [CS], miscarriage, hemorrhage, low placental adhesion, and preterm delivery) are statistically elevated in women with endometriosis. Furthermore, ruptured ovarian endometrioma, appendicitis, intestinal perforation, and hemoperitoneum have been described in pregnancy. Obstetricians are largely unfamiliar with these complications, as they have not been thoroughly investigated. The development and pathogenesis of endometriosis is an important field of study and has not yet been fully elucidated. Finding these mechanisms is crucial for the development of new and more effective strategies to treat this condition. Endometriosis can have an impact on obstetric and neonatal outcomes of pregnancy, in addition to its potential effects on conception. To date, no additional monitoring is recommended for pregnancies with a history of endometriosis. However, more studies are urgently needed to assess the need for the tailored pregnancy monitoring of women with endometriosis.

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Condition tags

endometriosisendometrioma

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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Cited by (10)

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