Konstantinos Nikolettos

Leptin and visfatin are adipokines involved in metabolic regulation and fetal development, but their associations with maternal gestational diabetes mellitus and neonatal growth remain incompletely understood. This study investigated the re…

Kisspeptins play a crucial role in the normal functioning of the reproductive axis in both humans and animals by stimulating the secretion of gonadotropin-releasing hormone (GnRH) from the hypothalamus. Recent studies have investigated the …

Pelvic tumors, especially those in difficult locations such as tumors in the rectouterine pouch in contact with the sigmoid colon, pose therapeutic approach difficulties due to the increased risk of complications, such as intestinal perfora…

Objective: Oophorectomy is a common procedure for benign uterine conditions, historically recommended for women aged 40-45 and older due to the belief that ovarian preservation had no significant benefits. This review evaluates the literatu…

Background/Objectives: Endometriosis is characterized by the presence of ectopic endometrial-like glands and stroma outside the endometrial cavity, which mainly occurs in the pelvic cavity. Pulmonary endometriosis, or thoracic endometriosis…

BACKGROUND: Reproduction ability requires a certain amount of body fat that is necessary for ovulation, menstruation and pregnancy. Fat tissue represents an endocrine organ with high metabolic activity as it produces adipokines such as lept…

Adenomyosis is characterized by ectopic proliferation of endometrial tissue within the myometrium. Histologically, this condition is marked by the presence of islands of benign endometrial glands surrounded by stromal cells. The myometrium …

Despite the increased frequency of endometriosis, it remains one of the most enigmatic disorders regarding its effects on pregnancy. Endometriosis adversely affects both natural and assisted conception. Impaired folliculogenesis, which caus…

BACKGROUND/AIM: To investigate the possible association of kisspeptin levels with the ovarian reserves of women of reproductive age. PATIENTS AND METHODS: Eighty women aged 19-40 participated after signing an informed consent. Of these, 74…

Uterine artery embolization (UAE) for the treatment of symptomatic uterine fibroids and non-controllable adenomyosis symptoms is a relatively new procedure for organ-preserving therapy. These benign conditions can become symptomatic in abou…

INTRODUCTION: Polycystic ovarian syndrome (PCOS) affects 5-20% of females and is the most common cause of anovulatory infertility. Leptin seems to have an important role in reproduction. Many reproductive pathologies such as preeclampsia, P…

Objectives: Fibroids cause significant morbidity and are the most common indication for hysterectomies worldwide, delimiting a major public health problem. Uterine artery embolization (UAE) is an alternative therapy to surgical treatment of…

Adenomyosis is characterized by the development of endometrial ectopic glands and tissue in the myometrium layer in depth greater than 2.5 mm from the endometrial surface of the separative area by -myomas well as by hypertrophy and hyperpla…

Uterine natural killer (uNK) cells constitute a unique uterine leucocyte subpopulation facilitating implantation and maintaining pregnancy. Herein, we critically analyze current evidence regarding the role of uNK cells in the events entaile…