Annals of medicine

BACKGROUND: To investigate the long-term systemic effects of tubal sterilisation using the silver clip technique, a commonly used yet understudied permanent contraceptive method, by evaluating its impact on inflammatory responses and coagul…

OBJECTIVES: Associations between carbohydrate and fiber intake and endometriosis (EM) have been inconsistent, and no study has evaluated the combined effect of the carbohydrate-to-fiber ratio (CFR) or its inflammatory mechanisms. MATERIALS…

OBJECTIVE: To describe clinical intrauterine insemination (IUI) outcomes among infertile patients with different infertility indications, and further compare reproductive outcomes between natural cycle (NC) and ovarian stimulation cycle (OS…

INTRODUCTION: Constipation and bloating are common bothersome gastrointestinal (GI) symptoms that frequently occur concurrently. It is important to recognize the underlying condition(s) and tailor therapeutic interventions appropriately. Th…

BACKGROUND: To develop and validate a risk prediction model for malignant transformation in patients with gallbladder polyps (GBPs) using an interpretable machine learning framework and evaluate its predictive accuracy. METHODS: A retrospe…

OBJECTIVES: This meta-analysis aimed to evaluate the association between endometriosis (EM) and cardiovascular disease (CVD) risk by synthesizing evidence from large-scale cohort studies, with emphasis on subtype-specific risks and geograph…

BACKGROUND: Alcohol withdrawal is a life-threatening complication of sudden cessation of alcohol intake in a dependent individual. Medicinal ethanol demonstrates promise in addressing the symptoms of severe alcohol withdrawal; however, its …

OBJECTIVES: To explore the correlation between different delivery methods for high-positioned fetal heads during cesarean section(CS) and obstetric complications. METHODS: A retrospective analysis of 236 cephalic-position CS patients with …

OBJECTIVE: This study aimed to investigate whether women with unilateral and bilateral OMA differ in anxiety symptoms, and secondarily in depressive symptoms and sexual dysfunction symptoms, and to evaluate the independent contribution of c…

BACKGROUND: Intrauterine adhesions (IUA), particularly moderate to severe cases, is a leading cause of decreased menstrual flow and secondary infertility in women, affecting an estimated 2.8%∼46% of infertile women. Hysteroscopy remains the…

PURPOSE: Adenomyosis (AM) with dysmenorrhea (AMD) is a global public health concern that may involve abnormal brain function and heightened vulnerability to anxiety and depression. This study aimed to investigate static and dynamic regional…

BACKGROUND: The concept of ferroptosis debuted as a newly defined programmed cell death in 2012. Among programmed cell death mechanisms, ferroptosis stands out as being fundamentally dependent on iron. At the heart of this mechanism lies th…

BACKGROUND: The incidence of malignant tumors/precancerous lesions is rising, yet their impact on pregnancy outcomes in women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) remains unclear. METHODS: A single-…

BACKGROUND: Protein palmitoylation is a significant post-translational modification that influences protein stability, localization, and signaling through the addition of palmitoyl groups to cysteine, serine/threonine, or lysine residues. I…

BACKGROUND: Endometriosis, a chronic immune-mediated inflammatory disease, remains elusive in its pathogenesis. Given vitamin D (VD)'s pivotal role in modulating innate and adaptive immune responses, we sought to elucidate how VD modulates …

ObjectiveTo evaluate the accuracy of multimodal vaginal ultrasound in assessing post-caesarean scar healing.MethodsA systematic review and meta-analysis were conducted on Chinese and English studies using multimodal vaginal ultrasound to di…

BACKGROUND: The potentially risky effects of metabolites of phthalates (mPAEs) on inflammation and immune function have attracted much attention in recent years. However, direct studies on the relationship between these metabolites and the …

OBJECTIVE: To identify clinical characteristics and risk factors for adverse pregnancy outcomes after clinical pregnancy following laparoscopic tubal anastomosis (LTA). METHODS: Retrospective analysis of 253 patients undergoing LTA (May 20…

OBJECTIVE: To evaluate preoperative serum calcium levels and their association with deep infiltrating endometriosis (DIE) in ovarian endometrioma. DESIGN: A retrospective, observational cohort study. PARTICIPANTS: A total of 2,557 women w…

BACKGROUND: Extrinsic adenomyosis exhibits heterogeneous clinical symptoms, with pain being more commonly reported. The relationship between magnetic resonance imaging (MRI) feature and symptom remains unclear. OBJECTIVE: To evaluate the p…

BACKGROUND/INTRODUCTION: Antimicrobial resistance (AMR) and the evolution of multiple drug-resistant (MDR) bacteria is of grave public health concern. To combat the pandemic of AMR, it is necessary to focus on novel alternatives for drug de…