Fahad T. Alotaibi

ORCID: 0000-0002-4237-9464 · 14 papers in corpus · active 2015-2025

Study types

  • article 9
  • other 3
  • review 2

Condition tags

  • endometriosis 14
  • mesh:D004715 11
  • dyspareunia 5
  • die_deep_infiltrating 4
  • endometrioma 4
  • mesh:D004414 3
  • bowel_endometriosis 3
  • mesh:D017699 2
  • mesh:D004412 1
  • infertility 1
review 2025
International journal of molecular sciences ·doi:10.3390/ijms26135998

Endometriosis is a complex gynecological disorder characterized by the presence of endometrial-like tissue outside the uterus, leading to chronic pain and infertility. Immunohistochemistry (IHC) serves as a vital technique for elucidating t…

article 2024
Biomolecules ·doi:10.3390/biom14050583

Endometriosis is a gynecological disorder associated with local inflammation and neuroproliferation. Increased nerve bundle density has been attributed to increased expression of nerve growth factor (NGF) and interleukin-1β (IL-1β). Immunoh…

article 2024
Human Reproduction ·doi:10.1093/humrep/deae269

STUDY QUESTION: Is there an association between the somatic loss of PTEN (phosphatase and tensin homolog) and ARID1A (AT-rich interaction domain 1A) and endometriosis disease severity and worse clinical outcomes? SUMMARY ANSWER: Somatic PTE…

article 2023
Frontiers in reproductive health ·doi:10.3389/frph.2023.1297986

Introduction We propose a standardized protocol for measurement of nerve bundle density in endometriosis as a potential biomarker, including in deep endometriosis (DE), ovarian endometriomas (OMA) and superficial peritoneal endometriosis (S…

article 2022
F&S science ·doi:10.1016/j.xfss.2022.09.004

OBJECTIVE: To study the role of interleukin (IL)-1β and the plasminogen activating (PA) system members in endometriotic stromal cell (ESC) migration/invasion. DESIGN: Primary cultures of ESCs. SETTING: Tertiary referral center for endomet…

other 2020
Cell reports ·doi:10.1016/j.celrep.2020.108366

Endometriosis affects 1 in 10 women and is characterized by the presence of abnormal endometrium at ectopic sites. ARID1A mutations are observed in deeply invasive forms of the disease, often correlating with malignancy. To identify epigene…

other 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00167-w

Endometriosis is characterized by the presence of ectopic endometrial tissues. Mechanisms of tissue dissemination in endometriosis may be similar to those involved in tumor metastasis. We hypothesize that dysregulation of kisspeptin (KISS1)…

review 2020
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2020.05.009
article 2020
Human Reproduction ·doi:10.1093/humrep/deaa017

STUDY QUESTION: Does interleukin-1β (IL-1β) play a role in promoting nerve growth factor expression, neurogenesis and deep dyspareunia in endometriosis? SUMMARY ANSWER: IL-1β directly stimulates nerve growth factor (NGF) expression in endom…

article 2019
·doi:10.14288/1.0380848

CONTEXT; Deep dyspareunia (pelvic pain with sexual intercourse) affects half of women with endometriosis, but the underlying mechanisms are unclear. OBJECTIVE: To investigate whether nerve growth factor (NGF) and its receptor (TrkA/p75NTR) …

other 2019
PloS one ·doi:10.1371/journal.pone.0219064

PURPOSE: Deep infiltrating endometriosis (DIE) is defined as an endometriotic lesion penetrating to a depth of >5 mm and is associated with pelvic pain, but the underlying mechanisms are unclear. Our objective is to investigate whether plas…

article 2017
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117716778
article 2017
·doi:10.14288/1.0340309

Endometriosis is a disease that affects almost 10% of reproductive-age women, where 50 % of these women have pelvic pain with sexual intercourse. Deep endometriosis is defined as an endometriotic lesion penetrating to a depth of 5 mm or mor…

article 2015
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115623644