Ovarian Reserve in Patients with Endometriosis
Endometriosis and cystectomy for endometriomas may negatively impact ovarian reserve through chronic inflammation or direct damage, affecting fertility outcomes.
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This chapter reviews the physiology of ovarian reserve and discusses how diminished ovarian reserve is a major concern in women with endometriosis-associated infertility. It summarizes evidence that ovarian reserve may be affected by endometriomas themselves and by surgical cystectomy, including findings that postoperative ovarian response can be poor and that chronic pelvic inflammation may influence dormant follicles in the ovarian cortex. The chapter also notes that ovarian reserve testing using measures such as anti-Müllerian hormone (AMH) and antral follicle count (AFC) is used increasingly, but it frames these tests within the accumulating (and potentially indirect) understanding of follicle maintenance mechanisms. This paper is centrally about endometriosis — it focuses on how endometriosis and endometrioma-related treatment may diminish ovarian reserve and thereby contribute to infertility.
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Cited by (4)
- Analysis of factors associated with ovarian reserve in a group of poor responders to in vitro fertilization: A cross-sectional study 2020
- Morphologic study of the excised ovarian tissue in women with the recurrence of ovarian endometriosis after laparoscopic cystectomy 2015
- The impact of previous ovarian surgery on ovarian reserve in patients with endometriosis 2015
- Endometriosis 2014
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