Radionuclide hysterosalpingography is not a reliable tool for investigation of fallopian tube transport--a controlled randomized study using particles of two sizes during three different parts of the menstrual cycle

Kjell Wånggren; Håkan Wramsby; H. Wramsby; Staffan Bremmer; Steffan Lundberg; Hans Jacobsson

doi:10.1159/000321795

Radionuclide hysterosalpingography is not a reliable tool for investigation of fallopian tube transport--a controlled randomized study using particles of two sizes during three different parts of the menstrual cycle

Kjell Wånggren, Håkan Wramsby, H. Wramsby, Staffan Bremmer, Steffan Lundberg, Hans Jacobsson

Gynecologic and obstetric investigation · 2010 · vol. 72(1) , pp. 20–24 · doi:10.1159/000321795 · PMID:21196688 · W2062623108

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Radionuclide hysterosalpingography using particles of two sizes during three menstrual cycle phases was inconclusive, suggesting it is not a reliable tool for investigating fallopian tube transport.

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Abstract

BACKGROUND/AIMS: Earlier studies with radionuclide hysterosalpingography (RN-HSG) using either small or large particles have shown different results. Some studies have questioned the clinical relevance of RN-HSG. The aim of this study was to evaluate the RN-HSG method using two different sizes of radio-labelled particles during different parts of the menstrual cycle. METHODS: Ten healthy women, 28-40 years of age (mean 34.5), with proven fertility, regular menstrual cycle, not using oral contraceptives and due to undergo laparoscopic sterilization, were randomized to RN-HSG after deposition of a solution with either small Albures or large MAASOL, (99m)Tc-radio-labelled particles into the cervix uteri. Investigations were, for every patient, performed during the follicular, peri-ovulatory and mid-luteal parts of the menstrual cycle. Transport of radioactivity from cervix to uterus and Fallopian tubes was evaluated. RESULTS: The RN-HSG investigations could not show any difference between the two different sizes of radio-labelled particles. Transport of radioactivity to the Fallopian tube was seen only in some cases and most frequently during the peri-ovulatory period. CONCLUSION: We found the RN-HSG investigations inconclusive. The RN-HSG method does not seem to be a reliable tool for the investigation of Fallopian tube transport.

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MeSH descriptors

Fallopian Tubes Menstrual Cycle Uterus Adult Biological Transport Fallopian Tube Patency Tests Fallopian Tube Patency Tests Fallopian Tubes Female Humans Hysterosalpingography Particle Size Radionuclide Imaging Technetium Uterus

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References (18)

Oxytocin--a stimulator of directed sperm transport in humans via openalex
The anatomical basis for a possible counter current exchange mechanism in the human adnex via openalex
doi:10.1093/humrep/12.2.275 via openalex
doi:10.1093/humrep/11.3.627 via openalex
doi:10.1016/s0015-0282(97)00467-6 via openalex
doi:10.1016/s0001-2998(81)80027-x via openalex
doi:10.1016/s0015-0282(01)02905-3 via openalex
W2416107101 via openalex
doi:10.1093/humupd/4.5.655 via openalex
doi:10.1093/humupd/4.5.667 via openalex
doi:10.1016/j.fertnstert.2003.12.016 via openalex
doi:10.1159/000292590 via openalex
doi:10.1159/000293037 via openalex
doi:10.1093/oxfordjournals.humrep.a137373 via openalex
doi:10.1016/s0301-2115(02)00463-3 via openalex
doi:10.1111/j.1749-6632.1997.tb48550.x via openalex
doi:10.1016/0020-7292(89)90544-4 via openalex
doi:10.1016/j.ejogrb.2003.07.003 via openalex

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[1] Oxytocin--a stimulator of directed sperm transport in humans 2007

[2] The anatomical basis for a possible counter current exchange mechanism in the human adnex 1977