Gynecologic and obstetric investigation

Gynecol Obstet Invest · ISSN (e) 1423-002X · 444 papers in corpus
observational 2026
doi:10.1159/000546754 ·PMID:40532674

OBJECTIVES: The objective of the study was to evaluate the impact of male human papillomavirus (HPV) sexually transmitted infection on sperm parameters, embryo morphokinetics, and clinical pregnancy outcomes in assisted reproductive technol…

meta-analysis 2026
doi:10.1159/000551182 ·PMID:41758738

BACKGROUND: Dysmenorrhea is a debilitating symptom in patients with endometriosis, contributing significantly to disease burden. While the relationship between body mass index (BMI) and dysmenorrhea in these patients is unclear, emerging ev…

rct 2026
doi:10.1159/000546198 ·PMID:40341516

OBJECTIVES: Endometriosis is a chronic gynecological condition characterized by abnormal angiogenesis and cell adhesion processes driven by VEGF-VEGFR-2 signaling. cabergoline, a dopamine agonist, has been shown to inhibit angiogenesis in e…

case-report 2026
doi:10.1159/goi/aczag004 ·PMID:42671979

OBJECTIVES: Cecoappendiceal endometriosis is rare and frequently mimics colorectal neoplasia, making preoperative diagnosis challenging. We report the first documented case of a true cecal traction diverticulum caused directly by endometrio…

meta-analysis 2026
doi:10.1159/000550420 ·PMID:41729769

INTRODUCTION: Investigation of the number of oocytes recovered from different ovarian stimulation (OS) protocols is essential, as oocyte number is positively associated with the number of good-quality embryos obtained; however, there are fe…

meta-analysis 2026
doi:10.1159/000545414 ·PMID:40288359

UNLABELLED: Introduction: In recent years, dietary supplements have emerged as popular "natural" alternatives to conventional pharmacological treatments for various conditions, including endometriosis. The growing popularity of supplements …

lab-animal 2026
doi:10.1159/000545947 ·PMID:40319865

INTRODUCTION: The objective of this study was to examine the impact of semaphorin 3F (SEMA3F) on the proliferation, migration and ferroptosis of endometrial stromal cells in patients with endometriosis (EMS). METHODS: This study collected …

observational 2026
doi:10.1159/000546442 ·PMID:40373756

UNLABELLED: Objectives: Alterations in 17β-estradiol metabolism are known to potentially impair endometrial receptivity. Previous pioneering studies have investigated the role of endometrial steroid metabolism by determining steroid hormone…

observational 2026
doi:10.1159/000552113 ·PMID:42166394

OBJECTIVES: Endometriosis and endometrial polyps are both estrogen-dependent conditions, and an association between these two pathologies has been observed in infertile women. Our research question was: "Is there an association between endo…

observational 2026
doi:10.1159/000551682 ·PMID:41926545

OBJECTIVES: The objectives of the study were to evaluate the association between endometriosis, anxiety, allergic rhinoconjunctivitis, and asthma in hospitalized women and to determine the role of age. DESIGN: A cross-sectional study using…

observational 2026
doi:10.1159/000553532 ·PMID:42430267

OBJECTIVES: The aim of the study was to develop and validate a novel model for predicting complications in minimally invasive hysterectomy and to define a standardized classification system, the Hysterectomy Complication Classes (HCCs). DE…

case-report 2026
doi:10.1159/000553084 ·PMID:42313707

INTRODUCTION: Postpartum hemorrhage (PPH) remains one of the leading causes of maternal mortality worldwide. A rare but potentially life-threatening cause of secondary PPH is uterine artery pseudoaneurysm (UAP). In this case report, we pres…

lab-animal 2026
doi:10.1159/goi/aczag005 ·PMID:42678895

OBJECTIVES: The aim of this study was to examine SEMA3C expression in endometriosis (EMs) and its relationship with ferroptosis in human endometrial stromal cells (HESCs). DESIGN: This experimental study used patient tissue samples and in …

observational 2026
doi:10.1159/000550102 ·PMID:41811998

OBJECTIVES: The objective of this study was to evaluate whether ultrasound-based #Enzian classification predicts pain profiles and response to hormonal therapy in patients with endometriosis. Endometriosis is a chronic inflammatory disease …

meta-analysis 2026
doi:10.1159/000552625 ·PMID:42319865

INTRODUCTION: Endometriosis is characterized by a persistent inflammatory process and is commonly shown to be associated with pelvic pain, dysmenorrhea, and a deterioration in overall quality of life. Due to limitations and side effects of …

other 2025
doi:10.1159/000542074 ·PMID:39561733

OBJECTIVE: Various gonadotropins are used for ovarian stimulation (OS). This study investigated the cost-effectiveness of different gonadotropins based on real-world data from the French National Health Database (SNDS) over a 7-year follow-…

review 2025
doi:10.1159/000543075 ·PMID:39799937

BACKGROUND: Endometriosis is a chronic disease characterized by endometrial-like tissue outside the uterus. Superficial endometriosis (SE) is the most prevalent form, yet it remains underdiagnosed due to subtle clinical and imaging presenta…

observational 2025
doi:10.1159/000542825 ·PMID:39608323

OBJECTIVE: The increasing rate of cesarean sections (CSs) raises concerns over severe intra-abdominal adhesions, which are associated with numerous complications. We aimed to identify risk factors and predictive tools for severe adhesions. …

observational 2025
doi:10.1159/000543910 ·PMID:39978328

OBJECTIVES: The aim of this study was to investigate the clinical characteristics of women with superficial peritoneal endometriosis (SUP) diagnosed by surgery and not confirmed by histology, compared with histologically proven SUP. DESIGN…

other 2025
doi:10.1159/000548292 ·PMID:40920614
observational 2025
doi:10.1159/000547069 ·PMID:40555209

UNLABELLED: Objectives: The aim of this study was to evaluate the diagnostic accuracy of pelvic magnetic resonance imaging (MRI) interpreted using the #Enzian classification system by comparing MRI findings with laparoscopic outcomes in wom…

other 2025
doi:10.1159/000541380 ·PMID:39307128

OBJECTIVES: This study aimed to conduct a bibliometric analysis of research on endometriosis and infertility, focusing on the 100 most-cited (TOP100) articles in the literature. DESIGN: The design of this study is a bibliometric analysis. …

observational 2025
doi:10.1159/000542049 ·PMID:39496254

OBJECTIVE: In recent years, several studies have proposed an association between endometriosis and various cardiovascular diseases. Our study evaluated the association between endometriosis and atherosclerosis in patients under 35 years of …

observational 2025
doi:10.1159/000545204 ·PMID:40188811

UNLABELLED: Objective: Our study focused on evaluating a possible relationship between endometriosis, Raynaud's syndrome, or migraine among women. DESIGN: This was a cross-sectional population-based study. Participants/Materials; Setting; …

other 2025
doi:10.1159/000542408 ·PMID:39571567

OBJECTIVES: We aimed to determine the prevalence of female infertility in 204 countries and territories from 1990 to 2019. DESIGN: We evaluated the female infertility global burden between 1990 and 2019 in this systematic study. MATERIALS…