Use of Dienogest or Gonadotropin Releasing Hormone Agonist with Add back Hormone Therapy in Longterm Endometriosis Medical Management
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This review discusses the long-term use of dienogest or GnRH agonists with add-back therapy for endometriosis recurrence, focusing on adolescents and young adults.
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Abstract
Since endometriosis is a recurrent disease one needs longterm treatment for prevention of recurrence.2commonly used drugs for same are dienogest and gonadotropin releasing hormone agonists. There is not much experience with dienogest use, although enough experience exists regarding GnRH agonists. Important is to use add back hormone therapy with these agonists to prevent undesirable side effects. Rest selection of either of the drugs depends on cost, patient preference, drs experience, therapeutic effectiveness, tolerability and patients compliance expected. Thus we discuss the role of each agent in use for longterm endometriosis recurrence and in case of adolescents and patients presenting with endometriosis in young adults needing longterm therapy.
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