Massive cystic degeneration of a uterine leiomyoma in a patient with autosomal dominant polycystic kidney disease

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This paper describes a rare case of a uterine leiomyoma with massive cystic degeneration in a patient with autosomal dominant polycystic kidney disease, where the uterine cyst was suspected to be an extrarenal manifestation.

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Abstract

BACKGROUND: A uterine cyst occurring as an extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD) is extremely rare. CASE: A 46-year-old Japanese woman was referred with a large abdominal mass causing severe abdominal distension. A large uterine cyst as an extrarenal manifestation of ADPKD was strongly suspected. First, we managed this patient by aspirating the cyst fluid through a small laparotomy. A year later, the cyst recurred and the patient underwent hysterectomy. Massive cystic degeneration of a uterine leiomyoma was diagnosed histologically. CONCLUSION: We described the rare case of massive cystic degeneration of a uterine leiomyoma in a patient with ADPKD, in which a causal relationship was suspected.

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MeSH descriptors

Leiomyoma Polycystic Kidney, Autosomal Dominant Uterine Neoplasms Cysts Female Humans Hysterectomy Laparotomy Leiomyoma Leiomyoma Leiomyoma Middle Aged Neoplasm Recurrence, Local Polycystic Kidney, Autosomal Dominant Uterine Neoplasms Uterine Neoplasms Uterine Neoplasms

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openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:15:04.544443+00:00
License: CC0 · commercial use OK