Reproductive and Menstrual Risk Factors for Endometriosis Disease: A Case-Control Study

Sanaz Mollazadeh, Mahin Kamalifard, Behnaz Sadeghzadeh Oskouei, Nayyereh Aminisani, Mehri Jafari Shobeiri, Mojgan Mirghafourvand‬‬‬‬‬‬‬‬‬‬‬‬‬‬
In: Crescent Journal of Medical and Biological Sciences · 2019 · vol. 9(1) , pp. 43–50 · doi:10.34172/cjmb.2022.08 · W4213227392
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This case-control study found that early menarche, no pregnancy or lactation history, irregular/prolonged menstruation, and painful intercourse are significantly associated with endometriosis.

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Abstract

Objectives: The endometriosis prevalence in the general population is about 7%-10%. In 30% of women, endometriosis is one of the causes of primary and secondary infertility. There are various risk factors for this disease. The present study aimed to determine the reproductive and menstrual risk factors of endometriosis. Materials and Methods: In this case-control study, 185 women of reproductive age with confirmed endometriosis were compared with 370 women of reproductive age who referred to the same center for other problems in terms of reproductive and menstruation risk factors for endometriosis. The two groups were matched for age. Data were collected using a researcher-made questionnaire based on previous studies. Finally, bivariate analysis was done by the chi-square test, and multivariate analysis was performed by the conditional logistic regression for controlling confounder variables. Results: Based on multivariate logistic regression, early menarche age (P=0.004), no history of pregnancy (P<0.001), no child (P=0.002), no lactation history (P<0.001), high age of the first lactation (P=0.029), short duration of breastfeeding (P=0.015), no regular menstruation (P<0.001), short intervals between menstrual bleedings (P=0.016), prolonged menstruation (P<0.001), dysmenorrhea (P<0.001), dyspareunia (P<0.001), and recurrent vaginitis (P<0.001) had a significant relationship with endometriosis. Conclusions: In general, there was a relationship between some reproductive and menstrual characteristics and endometriosis. Therefore, it seems that these characteristics can predict the occurrence of endometriosis disease.
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Jan 2022, Vol 9, Issue 1 Advanced Search For Author's & Reviewer's Poll How do you find the scientific quality of the published articles on our web site? | Original Article | | | Reproductive and Menstrual Risk Factors for Endometriosis Disease: A Case-Control Study | | | Sanaz Mollazadeh1, Mahin Kamalifard2, Behnaz Sadeghzadeh Oskouei2, Nayyereh Aminisani3, Mehri Jafari Shobeiri4, Mojgan Mirghafourvand5 | | | 1Students’ Research Committee, Nursing and Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran 2Nursing and Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran 3Faculty of Health, Tabriz University of Medical Sciences, Tabriz, Iran 4Medicine Faculty, Tabriz University of Medical Sciences, Tabriz, Iran 5Social Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran | | | CJMB 2022; 9: 043-050 DOI: 10.34172/cjmb.2022.08 Viewed : 4453 times Downloaded : 3064 times. Keywords : Case-control study, Reproductive characteristics, Menstrual characteristics, Endometriosis | | | Full Text(PDF) | Related Articles | | | Abstract | | Objectives: The endometriosis prevalence in the general population is about 7%-10%. In 30% of women, endometriosis is one of the causes of primary and secondary infertility. There are various risk factors for this disease. The present study aimed to determine the reproductive and menstrual risk factors of endometriosis. Materials and Methods: In this case-control study, 185 women of reproductive age with confirmed endometriosis were compared with 370 women of reproductive age who referred to the same center for other problems in terms of reproductive and menstruation risk factors for endometriosis. The two groups were matched for age. Data were collected using a researcher-made questionnaire based on previous studies. Finally, bivariate analysis was done by the chi-square test, and multivariate analysis was performed by the conditional logistic regression for controlling confounder variables. Results: Based on multivariate logistic regression, early menarche age (P = 0.004), no history of pregnancy (P < 0.001), no child (P = 0.002), no lactation history (P < 0.001), high age of the first lactation (P = 0.029), short duration of breastfeeding (P = 0.015), no regular menstruation (P < 0.001), short intervals between menstrual bleedings (P = 0.016), prolonged menstruation (P < 0.001), dysmenorrhea (P < 0.001), dyspareunia (P < 0.001), and recurrent vaginitis (P < 0.001) had a significant relationship with endometriosis. Conclusions: In general, there was a relationship between some reproductive and menstrual characteristics and endometriosis. Therefore, it seems that these characteristics can predict the occurrence of endometriosis disease. | Cite By, Google Scholar Articles by Mollazadeh S Articles by Kamalifard M Articles by Sadeghzadeh Oskouei B Articles by Aminisani N Articles by Jafari Shobeiri M Articles by Mirghafourvand M Articles by Sanaz Mollazadeh Articles by Mahin Kamalifard Articles by Behnaz Sadeghzadeh Oskouei Articles by Nayyereh Aminisani Articles by Mehri Jafari Shobeiri Articles by Mojgan Mirghafourvand Submit Paper Online Submission System CJMB ENDNOTE ® Style Tutorials Publication Charge Medical and Biological Research Center About Journal Online Submission System CJMB ENDNOTE ® Style Tutorials Publication Charge Medical and Biological Research Center About Journal Publication Information Publisher Aras Part Medical International Press Editor-in-Chief Arash Khaki Deputy Editor Zafer Akan Aras Part Medical International Press Editor-in-Chief Arash Khaki Deputy Editor Zafer Akan Published Article Statistics

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endometriosisdysmenorrheadyspareuniainfertility

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