Embryo quality before and after surgical treatment of endometriosis in infertile patients

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Surgical treatment of endometriosis in infertile patients did not alter embryo quality on day 3, although live birth rates improved after surgery.

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This retrospective study evaluated 30 infertile patients who underwent IVF before and after surgical treatment for endometriosis, using only IVF cycles with similar stimulation protocols and treating patients as their own controls. Embryo quality on day 3 was assessed by standard visual evaluation, and the authors compared findings before versus after surgery. Embryo quality on day 3 was similar in the pre- and post-surgery cycles, and live birth was observed after the IVF cycle following surgery in 43% of patients, with no live births after the first IVF cycle. This paper is centrally about endometriosis — it tests whether surgery for endometriosis changes embryo quality in infertile IVF patients.

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Abstract

Purpose To investigate the hypothesis that surgical treatment of endometriosis in infertile patients may improve pregnancy rates by improving embryo quality.

Methods

We conducted a retrospective evaluation of 30 infertile patients treated with in vitro fertilization (IVF) before and after surgery for endometriosis. Patients served as their own controls and only cycles with similar stimulation protocols were compared.

Results

Using standard visual evaluation, embryo quality on day 3 was similar before and after surgical treatment of endometriosis. Fifty seven percent of patients had stage I–II endometriosis and 43% had stage III–IV disease. No patients had a live birth after the first IVF cycle and 43% of patients had a live birth with the IVF cycle after surgery.

Conclusions

Surgical treatment of endometriosis does not alter embryo quality in patients with infertility treated with IVF. Similar content being viewed by others

References

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Embryo, Mammalian Endometriosis Infertility, Female Adult Disease Progression Embryo, Mammalian Endometriosis Endometriosis Endometriosis Female Fertilization in Vitro Humans Infertility, Female Infertility, Female Pregnancy Pregnancy Outcome Pregnancy Rate Retrospective Studies

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