Hypoxia-inducible factor-1alpha: A promising therapeutic target in endometriosis
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This paper explores hypoxia-inducible factor-1alpha (HIF-1α) as a potential therapeutic target for endometriosis, based on its role in disease pathology.
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References (95)
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Cited by (32)
- Hypoxia-induced regulations of cell adhesion molecules and their implications for pathogenesis, diagnosis, and treatment of endometriosis 2026
- Hypoxia-mediated epigenetic silencing of YTHDF2 promotes endometriosis progression via the NFE2L1-NF-κB axis 2026
- A cRGD-modified liposome for targeted delivery of artesunate to inhibit angiogenesis in endometriosis 2025
- Warburg-like Metabolic Reprogramming in Endometriosis: From Molecular Mechanisms to Therapeutic Approaches 2025
- How transcription factors regulate apoptosis in endometriosis (Review) 2025
- Atypical endometriosis and the progression to endometriosis-associated ovarian cancer: an updated review 2025
- HIF-1α regulates DcR3 to promote the development of endometriosis 2024
- The “Road” to Malignant Transformation from Endometriosis to Endometriosis-Associated Ovarian Cancers (EAOCs): An mTOR-Centred Review 2024
- Hypoxia-induced Semaphorin 3A promotes the development of endometriosis through regulating macrophage polarization 2024
- Zinc deficiency is associated with the development of ovarian endometrial cysts. 2023
- Inflammatory Cytokine-Induced HIF-1 Activation Promotes Epithelial–Mesenchymal Transition in Endometrial Epithelial Cells 2023
- Downregulating HK2 inhibits proliferation of endometrial stromal cells through a noncanonical pathway involving phosphorylation of signal transducer and activator of transcription 1 in endometriosis 2022
- Therapeutic Strategies Focused on Cancer-Associated Hypercoagulation for Ovarian Clear Cell Carcinoma 2022
- miR‑143‑3p inhibits endometriotic stromal cell proliferation and invasion by inactivating autophagy in endometriosis 2021
- Hypoxia‑induced lactate dehydrogenase A protects cells from apoptosis in endometriosis 2021
- Down-Regulating Hexokinase 2 Inhibits Proliferation of Endometrial Stromal Cells Through a Noncanonical Pathway Involving Phosphorylated-STAT1 in Endometriosis 2021
- Immunology and Immunotherapy of Endometriosis 2021
- Upregulation of the long noncoding RNA UBOX5 antisense RNA 1 (UBOX5-AS1) under hypoxic conditions promotes epithelial-mesenchymal transition in endometriosis 2021
- The Role of Long Non-Coding RNAs in Endometriosis 2021
- Circ_0007331 knock‐down suppresses the progression of endometriosis via miR‐200c‐3p/HiF‐1α axis 2020
- MiR-210-3p protects endometriotic cells from oxidative stress-induced cell cycle arrest by targeting BARD1 2019
- Identification of differentially expressed genes and signaling pathways involved in endometriosis by integrated bioinformatics analysis 2019
- Genomic Function of Estrogen Receptor β in Endometriosis 2019
- Autophagy contributes to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis† 2018
- The Endometriotic Tumor Microenvironment in Ovarian Cancer 2018
- Pathogenesis of endometriosis: the genetic/epigenetic theory 2018
- Long non‐coding <scp>RNA MALAT</scp>1 mediates hypoxia‐induced pro‐survival autophagy of endometrial stromal cells in endometriosis 2018
- Hypoxia Promotes Ectopic Adhesion Ability of Endometrial Stromal Cells via TGF-β1/Smad Signaling in Endometriosis 2018
- Autophagy in endometriosis: Friend or foe? 2017
- Overexpression of Four Joint Box-I Protein (FJXI) in Eutopic Endometrium From Women With Endometriosis 2017
- Hypoxia-inducible factor-1α promotes endometrial stromal cells migration and invasion by upregulating autophagy in endometriosis 2017
- Effect of rapamycin on endometriosis in mice 2016
Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:21:13.485820+00:00
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