Prediction of endometrial ablation success according to perioperative findings

M I Shamonki; Mousa Shamonki; William F. Ziegler; W F Ziegler; Gary J. Badger; G J Badger; Cynthia K. Sites; C K Sites

doi:10.1067/mob.2000.105393

Prediction of endometrial ablation success according to perioperative findings

M I Shamonki, Mousa Shamonki, William F. Ziegler, W F Ziegler, Gary J. Badger, G J Badger, Cynthia K. Sites, C K Sites

American journal of obstetrics and gynecology · 2000 · vol. 182(5) , pp. 1005–1007 · doi:10.1067/mob.2000.105393 · PMID:10819809 · W2159587878

Observational OA: closed CC0 ⤵ 3 in-corpus citations

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This study identified perioperative predictors of successful endometrial ablation outcomes.

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Abstract

OBJECTIVE: The aim of this study was to determine which factors in the perioperative period influence the success of endometrial ablation in alleviating menorrhagia. STUDY DESIGN: We performed a retrospective chart review of 120 women aged 27 to 49 years who underwent endometrial ablation after 2 months of preoperative treatment with danazol (Danocrine, 800 mg/d orally) or leuprolide (Lupron, 3.75 mg in one intramuscular injection each month). Patients who required medical management or additional operations to control the vaginal bleeding during follow-up (median follow-up, 37 weeks) were considered to have ablation failures. RESULTS: Sixty-three percent of patients (76/120) had a successful procedure. The chance of success was greater if a cavity of normal appearance was found (odds ratio, 2.3; P =.04). The finding of an intramural fibroid before the procedure resulted in a reduced trend toward success (odds ratio, 0.4; P =.06). The use of danazol pretreatment improved the rate of success overall (odds ratio, 2.2; P =.05) and especially among women <40 years old (P =.01) CONCLUSION: Perioperative findings may provide useful information in counseling patients regarding endometrial ablation. Success is greater among patients with a normal intrauterine cavity and after preoperative treatment with danazol.

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MeSH descriptors

Endometrium Leiomyoma Menorrhagia Treatment Outcome Uterine Neoplasms Adult Danazol Danazol Endometrium Estrogen Antagonists Estrogen Antagonists Female Humans Leiomyoma Leiomyoma Leuprolide Leuprolide Logistic Models Menorrhagia Menorrhagia

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Cites (4)

Cited by (3)

References (9)

An economic evaluation of transcervical endometrial resection versus abdominal hysterectomy for the treatment of menorrhagia via openalex
Depot goserelin and danazol pre-treatment before rollerball endometrial ablation for menorrhagia via openalex
Does endometrial resection help dysmenorrhea? via openalex
Resumption of menstruation after amenorrhea in women treated by endometrial ablation and myometrial resection via openalex
doi:10.1016/0029-7844(94)00326-9 via openalex
doi:10.1016/s0020-7292(98)00137-4 via openalex
doi:10.5694/j.1326-5377.1993.tb137573.x via openalex
doi:10.1016/0029-7844(96)00150-0 via openalex
doi:10.1016/s1074-3804(05)80114-8 via openalex

Cited by (3)

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[1] An economic evaluation of transcervical endometrial resection versus abdominal hysterectomy for the treatment of menorrhagia 1993

[2] Depot goserelin and danazol pre-treatment before rollerball endometrial ablation for menorrhagia 1996

[3] Does endometrial resection help dysmenorrhea? 1997

[4] Resumption of menstruation after amenorrhea in women treated by endometrial ablation and myometrial resection 1997