American journal of obstetrics and gynecology

BACKGROUND: Deep infiltrating endometriosis predominantly affects the posterior pelvic compartment and often requires complex surgical procedures, which are associated with a significant risk of postoperative complications. Limited evidence…

BACKGROUND: Persons diagnosed with endometriosis report deleterious effects to their physical, psychological, and relational well-being. While some couples state that these challenges extend beyond the person in pain to also affect their pa…

BACKGROUND: Women with endometriosis and adenomyosis have an increased risk of age-dependent diseases such as cardiovascular disease and cancer. Whether this reflects differences in biological age is unknown. OBJECTIVE: To compare the epig…

BACKGROUND: The 2020 Multicentre Abdominal vs Vaginal Randomised Intervention of Cerclage trial found that transabdominal cerclage placed via open laparotomy reduces the risk of spontaneous preterm birth before 32 weeks relative to transvag…

BACKGROUND: Understanding of the impact of endometriosis on adverse early pregnancy outcomes has evolved in recent decades and has been partly attributed to endocrine dysfunction and chronic inflammation. However, data from population-based…

BACKGROUND: While endometriosis is thought to be a heterogeneous disease, the pathophysiologic heterogeneity across the 3 visualized lesion macrophenotypes (ie, superficial peritoneal endometriosis lesions, endometriomas, and deep lesions) …

Uterine fibroids (leiomyomas or myomas) are a major issue for individuals with a uterus as well as a disease with profound disparities for Black/African American (Black) individuals. These disparities have roots in early gynecologic practic…

BACKGROUND: Among patients undergoing hysterectomy for benign indications, Black patients experience higher rates of perioperative complications across both abdominal and minimally invasive surgical routes. This disparity persists after adj…

BACKGROUND: Endometriosis is a chronic, gynecologic condition in which tissue similar to the lining of the uterus implants throughout the body. Women with endometriosis have a higher prevalence of infertility and a greater risk of early nat…

OBJECTIVE: Data on long-term outcomes of surgical management of rectal endometriosis are scarce and generally provided by cohort studies where choice of surgical technique is based on various uncontrolled factors with significant lost-to-fo…

BACKGROUND: Preterm birth is the leading cause of neonatal and infant mortality worldwide. Vaginal progesterone reduces the rate of preterm birth by approximately 45% in women with a singleton gestation and a mid-trimester sonographically s…

BACKGROUND: Obstetric complications linked to assisted reproductive technology could be confounded by underlying parental factors and were often derived from databases not designed to study these complications. With evolving assisted reprod…

BACKGROUND: Ovarian endometriosis is one of the most frequently diagnosed endometriosis subtypes. Surgical treatment may be required in selected cases, and indications for surgery have evolved over the years. However, recurrence is common a…

BACKGROUND: Postoperative pain following laparoscopic surgery can delay recovery and increase opioid use. Lower insufflation pressures have been consistently shown to reduce pain in general surgery procedures, but their impact in gynecologi…

OBJECTIVE: To systematically review and quantify the impact of adenomyosis on maternal, neonatal, and obstetric outcomes. DATA SOURCES: A comprehensive, unrestricted search was conducted in MEDLINE, Scopus, Embase, Literatura Latino-Americ…

Cesarean delivery, one of the most common surgeries performed worldwide, carries the risk of complications. These complications affect both mothers and newborns, but in this review, only maternal complications will be addressed. Clinical si…

BACKGROUND: Despite many available treatments for female chronic pelvic pain, there is limited patient success, engagement, or compliance with therapy. No current methods allow providers to effectively collect and integrate patient perspect…

BACKGROUND: It is unknown to what extent the surgical management of endometriosis occurs in the outpatient settings and which factors are associated with ambulatory vs inpatient surgical care. OBJECTIVE: The objective of this study was to …

BACKGROUND: Polycystic ovary syndrome is a common endocrine disorder, characterized by oligomenorrhea and androgen excess. Only a few studies have addressed the natural history of menstrual cycles among women with polycystic ovary syndrome …

In 1995, Morris first described cesarean scar defect as an "isthmocele" by macroscopy following hysterectomy in women with prior cesarean delivery. Cesarean scar defect is associated with gynecological symptoms such as abnormal uterine blee…

BACKGROUND: Vaginal lubricants are commonly used during sexual activity and clinical procedures such as transvaginal ultrasound. Epidemiologic and laboratory studies indicate hyperosmolal water-based lubricants may disrupt the vaginal micro…