Endometriosis and mental health disorders: identification and treatment as part of a multimodal approach

Anna Lena Zippl, Elisabeth Reiser, Beata Seeber
Fertility and sterility · 2023 · vol. 121(3) , pp. 370–378 · doi:10.1016/j.fertnstert.2023.12.033 · PMID:38160985 · W4390414883
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This review highlights the association between endometriosis and mental health disorders like anxiety and depression, suggesting a shared genetic predisposition and advocating for integrated medical and psychological care.

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Abstract

Endometriosis is a disease marked by more than just pain and infertility, as it transcends the well-characterized physical symptoms to be frequently associated with mental health issues. This review focuses on the associations between endometriosis and anxiety, depression, sexual dysfunction, and eating disorders, all of which show a higher prevalence in women with the disease. Studies show that pain, especially the chronic pelvic pain of endometriosis, likely serves as a mediating factor. Recent studies evaluating genetic predispositions for endometriosis and mental health disorders suggest a shared genetic predisposition. Healthcare providers who treat women with endometriosis should be aware of these associations to best treat their patients. A holistic approach to care by gynecologists as well as mental health professionals should emphasize prompt diagnosis, targeted medical interventions, and psychological support, while also recognizing the role of supportive relationships in improving the patient's quality of life.

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Condition tags

mesh:D004715mesh:D017699endometriosischronic_pelvic_paininfertility

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Depression Depression Depression Depression Depression Depression Depression Depression Female Female Female Female

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (76)

Cited by (20)

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