Oocyte Morphology and Reproductive Outcomes - Case Report and Literature Review

Raquel Meirelles Gaspar Coelho Guimarães, Raquel Meirelles Guimarães, Larissa Maciel Ribeiro, Lizandra Moura Paravidine Sasaki, Lizandra Paravidine Sasaki, Hitomi Miura Nakagawa, Hitomi Nakagawa, Iris Oliveira Cabral, I.O Cabral
JBRA assisted reproduction · 2021 · doi:10.5935/1518-0557.20210001 · W3137409295
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Abstract

Oocyte quality could be negatively affected by many factors including smoking, alcohol consumption, obesity, woman's age, endometriosis and controlled ovarian stimulation (COS), during assisted reproductive technology (ART), in addition to genetic factors, such as hormone receptor polymorphisms, for example. We know that the increase in the reactive oxygen species (ROS) due to systemic disorders causes biochemical and morphological changes to the oocytes, interfering with their quality. The oocyte dysmorphism can be expressed through intra and/or extra cytoplasmic changes. In general, the size and number of oocytes' morphological abnormalities are directly related to preimplantation development failure. This case report is based on four in vitro fertilization (IVF) cycles performed by a patient with oocyte dysmorphism in all oocytes captured. The literature review on this topic aims to relate the characteristics of the oocytes, presented in the case report, with research results about the quality and morphology of the oocytes.

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Condition tags

endometriosis

MeSH descriptors

Oocytes Ovulation Induction Female Fertilization in Vitro Humans Pregnancy Pregnancy Rate Reproductive Techniques, Assisted

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License: CC0 · commercial use OK