A within-patient comparison between superovulation with intra-uterine artificial insemination using husband's washed spermatozoa and gamete intrafallopian transfer in unexplained infertility

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This within-patient study compared superovulation with intrauterine insemination using husband's washed spermatozoa to gamete intrafallopian transfer for treating unexplained infertility.

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Abstract

The purpose of this study was to evaluate the success of gamete intrafallopian transfer (GIFT) and superovulation with intra-uterine artificial insemination (S-IUI) in couples with long-term unexplained infertility. Thirty-nine couples were offered three attempts at each treatment. Sixty-three IUI cycles were completed with a pregnancy rate of 1.5% per cycle. Forty-nine GIFT procedures were carried out with a pregnancy rate of 26.5% per cycle. The cumulative conception rate after three cycles of GIFT was 0.56. GIFT appears to offer a far greater chance of pregnancy than S-IUI in unexplained infertility.

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Condition tags

infertility

MeSH descriptors

Gamete Intrafallopian Transfer Infertility Insemination, Artificial, Homologous Superovulation Adult Buserelin Buserelin Clomiphene Clomiphene Female Humans Infertility Male Menotropins Menotropins Pregnancy Uterus

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openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:05:57.285809+00:00
License: CC0 · commercial use OK