The Uterine Peristaltic Pump

In: Advances in Experimental Medicine and Biology · 1997 · pp. 267–277 · doi:10.1007/978-1-4615-5913-9_49 · W122657059
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AI-generated summary by claude@2026-06+body, 2026-06-07

Uterine peristalsis, visualized by sonography, drives sperm transport to the fallopian tubes, with transport efficiency increasing with menstrual cycle progression and directed towards the dominant follicle.

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This paper studied uterine cervico-fundal peristaltic contractions and their role in rapid sperm transport across the female genital tract, using vaginal sonography and serial hysterosalpingoscintigraphy with labeled albumin macrospheres placed at the external cervical os across the follicular cycle. The authors found that contraction frequency (and presumably intensity) increases through the proliferative phase, with a greater proportion of inert macrospheres entering the uterine cavity and fallopian tubes at mid- and late follicular stages, and preferential transport into the tube ipsilateral to the dominant follicle without chemotaxis. They additionally reported that women with infertility and mostly mild endometriosis show uterine hyperperistalsis and midcycle dysperistalsis, which correlated with inert particle transport into tubes early in the follicular phase, and they explicitly propose a mechanical pathway for endometriosis development and possible sperm-transport disruption as a limitation of directed transport mechanisms. This paper is centrally about endometriosis — it directly examines uterine hyperperistalsis/dysperistalsis in women with mostly mild endometriosis and links these dysmotility patterns to potential retrograde transport of endometrial fragments.

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References

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New England Journal of Medicine 333: 1517–1521 Author information Authors and Affiliations Editor information Editors and Affiliations Rights and permissions Copyright information © 1997 Springer Science+Business Media New York About this chapter Cite this chapter Kunz, G., Beil, D., Deiniger, Н., Einspanier, A., Mall, G., Leyendecker, G. (1997). The Uterine Peristaltic Pump. In: Ivell, R., Holstein, AF. (eds) The Fate of the Male Germ Cell. Advances in Experimental Medicine and Biology, vol 424. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5913-9_49 Download citation DOI: https://doi.org/10.1007/978-1-4615-5913-9_49 Publisher Name: Springer, Boston, MA Print ISBN: 978-1-4613-7711-5 Online ISBN: 978-1-4615-5913-9 eBook Packages: Springer Book Archive

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