G. Leyendecker

Endometriosis is a common problem affecting 5-10% of women of childbearing age. It is a condition with unknown pathology, leaving us with several theories. However, about half of women with endometriosis complain of difficulty conceiving. T…

НАЦІОНАЛЬНА АКАДЕМІЯ МЕДИЧНИХ НАУК УКРАЇНИ ДЕРЖАВНА УСТАНОВА «ІНСТИТУТ ПЕДІАТРІЇ, АКУШЕРСТВА І ГІНЕКОЛОГІЇІМЕНІ АКАДЕМІКА О.М

© The Author(s) 2009. This article is published with open access at Springerlink.com Introduction This study presents a unifying concept of the pathophysiology of endometriosis and adenomyosis. In par-ticular, a physiological model is propo…

Purpose In a series of publications, we had developed the concept that uterine adenomyosis and pelvic endometriosis as well as endometriotic lesions at distant sites of the body share a common pathophysiology with endometriosis constituting…

PURPOSE: In a series of publications, we had developed the concept that uterine adenomyosis and pelvic endometriosis as well as endometriotic lesions at distant sites of the body share a common pathophysiology with endometriosis constitutin…

Pelvic endometriosis, deeply infiltrating endometriosis and uterine adenomyosis share a common pathophysiology and may be integrated into the physiological mechanism and new nosological concept of 'tissue injury and repair' (TIAR) and may, …

Pelvic endometriosis, deeply infiltrating endometriosis, and uterine adenomyosis share a common pathophysiology and may be integrated into the physiological mechanism and new nosological concept of “tissue injury and repair” and may, in thi…

The major authors of the last century described endometriosis as ectopic endometrial lesions occurring both in the uterus and in the peritoneal cavity, and the lesions were considered as variants of the same disease process. In the 1920s a …

INTRODUCTION: This study presents a unifying concept of the pathophysiology of endometriosis and adenomyosis. In particular, a physiological model is proposed that provides a comprehensive explanation of the local production of estrogen at …

Einleitung: Gewebeproben von peritonealer Endometriose, Adenomyose und von basalem Endometrium zeigten die gleichen zyklischen immunhistochemischen Veränderungen bezüglich der Hormonrezeptoren sowie der P-450 Aromatase*. Da beschrieben wurd…

The uterus is composed of different smooth muscle layers that serve various functions. First, menstrual debris is expulsed at the time of the menses. Second, sperm is transported in the preovulatory phase to maximize fertility, and third, t…

OBJECTIVE: Uterine hyperperistalsis and dysperistalsis are common phenomena in endometriosis and may be responsible for reduced fertility in cases of minimal or mild extent of disease. Since a high prevalence of adenomyosis uteri has been w…

BACKGROUND: The hypothesis is tested that there is a strong association between endometriosis and adenomyosis and that adenomyosis plays a role in causing infertility in women with endometriosis. METHODS. Magnetic resonance imaging of the u…

Peristaltic activity of the non-pregnant uterus serves fundamental functions in the early process of reproduction. Hyperperistalsis of the uterus is significantly associated with the development of endometriosis and adenomyosis. In women wi…

endometriums with endometriosis, which were labeled with Cy5-dUTP. Fluorescent labeled probes were hybridized on a microarray of 4800 human genes. Results: We could detect many genes expressed differently in eutopic endometrium with or with…