[Research Progress on Epigenetics in Endometriosis].

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AI-generated summary by claude@2026-06, 2026-06-08

This review examines the regulatory mechanisms and applications of epigenetic modifications, such as DNA methylation, histone modification, and non-coding RNAs, in the occurrence and development of endometriosis.

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AI-generated deep summary by claude@2026-06, 2026-06-09 · read from full text

This review article surveys current research on epigenetic mechanisms in endometriosis, focusing on how epigenetic regulation contributes to disease development and progression. It summarizes evidence across epigenetic layers (such as DNA methylation and histone-related regulation) and discusses how these changes can affect gene expression in endometriosis tissues. The paper’s main limitation is that, as a progress/review piece, it synthesizes findings rather than presenting new experimental data, and it relies on heterogeneous prior studies. This paper is centrally about endometriosis — specifically a research-progress review of epigenetics in endometriosis.

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Abstract

Epigenetics refers to heritable changes in gene expression and function without alterations in gene sequences,including DNA methylation,histone modification,and non-coding RNAs.Endometriosis is a benign gynecological disease that affects the fertility and health of reproductive-age women,the etiology of which remains unclear.The recent studies have demonstrated that epigenetics plays a key role in the occurrence and development of endometriosis.This article reviews the research progress in the regulatory mechanism and application of epigenetics in endometriosis.
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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis DNA Methylation DNA Methylation DNA Methylation DNA Methylation Epigenesis, Genetic Epigenesis, Genetic Epigenesis, Genetic Epigenesis, Genetic Female Female Female Female Humans Humans Humans

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Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-17T00:33:53.514047+00:00
License: CC0 · commercial use OK