Ruihui Lu

ORCID: 0000-0001-9212-3611 · 11 papers in corpus
lab-animal 2026
Chinese medical journal ·doi:10.1097/CM9.0000000000003770

BACKGROUND: Endometriosis (EMs) is one of the most common gynecologic diseases, and the roles of ferroptosis in EMs have not been fully clarified. The induction of ferroptosis has been demonstrated to inhibit the growth of ectopic lesions i…

lab-animal 2026
Nature communications ·doi:10.1038/s41467-026-69551-5

Endometriosis is a common gynecological disease associated with pelvic pain and infertility. Despite several existing theories, the etiology and molecular mechanisms of endometriosis remain to be investigated. Here we report that transcript…

observational 2025
European journal of medical research ·doi:10.1186/s40001-025-02816-9

BACKGROUND: This study aimed to investigate the effect of ovarian endometriosis (OE) on ovarian reserve, as well as on cumulative clinical pregnancy rates (cCPR) and cumulative live birth rates (cLBR) in groups of younger women (those under…

2024
·doi:10.1002/viw2.341
lab-animal 2024
Journal of genetics and genomics = Yi chuan xue bao ·doi:10.1016/j.jgg.2023.12.012

Endometriosis refers to as an estrogen-dependent disease. Estrogen receptor β (ERβ), the main estrogen receptor subtype which is encoded by the estrogen receptor 2 (ESR2) gene, can mediate the action of estrogen in endometriosis. Although s…

lab-animal 2024
Aging and disease ·doi:10.14336/ad.2024.0221

Diminished ovarian reserve (DOR) refers to a decrease in the number and/or quality of oocytes, leading to infertility, poor ovarian response and adverse pregnancy outcomes. Currently, the pathogenesis of DOR is largely unknown, and the effi…

review 2023
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae ·doi:10.3881/j.issn.1000-503x.14739

Epigenetics refers to heritable changes in gene expression and function without alterations in gene sequences,including DNA methylation,histone modification,and non-coding RNAs.Endometriosis is a benign gynecological disease that affects th…

lab-animal 2023
·doi:10.1002/viw.20230090

Abstract Transcription factor 21 (TCF21) and estrogen receptor beta (ERβ, encoded by ESR2) are highly expressed in endometriotic stromal cells (ESCs) and contribute to the pathogenesis of endometriosis. However, the exploration of TCF21 and…

review 2022
·doi:10.1097/rd9.0000000000000024

Endometriosis (EM) is a benign gynecological disease that affects the fertility and health of women of reproductive age; it is characterized by the presence of endometrial glands and stroma outside the uterine cavity. Although several hypot…

observational 2022
Journal of ovarian research ·doi:10.1186/s13048-022-01042-9

BACKGROUND: The possible impact of ovarian endometriomas (OMAs) on in vitro fertilization (IVF) outcomes remains controversial. Therefore, this study aimed to assess the impact of OMAs on IVF cycle parameters, including ovarian reserve and …

other 2021
Frontiers in endocrinology ·doi:10.3389/fendo.2021.717288

BACKGROUNDS: Despite the great advances in assisted reproductive technology (ART), poor ovarian response (POR) is still one of the most challenging tasks in reproductive medicine. This predictive model we developed aims to predict the indiv…