ENZIAN-Score, eine Klassifikation der tief infiltrierenden Endometriose

F Tuttlies, J Keckstein, U Ulrich, Marc Possover, M Possover, Karl-Werner Schweppe, K W Schweppe, M Wustlich, O Buchweitz, R Greb, R. R. Greb, O Kandolf, R Mangold, W Masetti, K Neis, K. J. Neis, G Rauter, Natalie Reeka, N Reeka, O Richter, A E Schindler, M Sillem, Martin Sillem, V Terruhn, H R Tinneberg, Hans‐Rudolf Tinneberg
Zentralblatt fur Gynakologie · 2005 · vol. 127(05) , pp. 275–281 · doi:10.1055/s-2005-836904 · PMID:16195969 · W1232911261
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

The ENZIAN-Score is a new classification system for deep infiltrating endometriosis, particularly in the retroperitoneum, using an oncological staging analogy to detail nodule location and extent.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-06 · read from full text ⓘ

The paper presents the ENZIAN-Score, a new classification system for deep infiltrating endometriosis, with particular focus on retroperitoneal manifestations of severe disease. It defines four stages analogous to oncologic staging, and further subdivides disease based on the localization and extent of endometriosis nodules. The authors report that the previously used rAFS-score lacks clinical suitability for meaningful categorization, supporting this claim with a retrospective analysis of their own patient cohort with severe intestinal endometriosis. This paper is centrally about endometriosis — specifically developing and evaluating the ENZIAN-Score classification for deep infiltrating disease, including retroperitoneal and intestinal involvement.

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Abstract

The ENZIAN-Score is presented as a new instrument to classify the deep infiltrating endometriosis. Especially the retroperitoneal part of the severe endometriosis is focussed on. In analogy to an oncological staging four different stages are pronounced. The localisation and the expansion of the endometriosis nodule was indicated to different subgroups. The still used rAFS-score is of no clinical evidence, as we pointed out in a retrospective study of our patients with severe intestinal endometriosis.
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Subscribe to RSS DOI: 10.1055/s-2005-836904 © Georg Thieme Verlag Stuttgart · New York ENZIAN-Score, eine Klassifikation der tief infiltrierenden Endometriose ENZIAN-Score, a classification of Deep Infiltrating EndometriosisPublication History Publication Date: 29 September 2005 (online) Zusammenfassung Mit dem ENZIAN-Score wird eine neue Klassifikation der tief infiltrierenden Endometriose vorgestellt. Es wird insbesondere auf die retroperitoneale Manifestation der schweren Endometrioseerkrankung Bezug genommen. Dabei werden 4 Stadien in Anlehnung an ein onkologisches Staging unterschieden. Weitere Untergruppen ergeben sich aus der Lokalisation und der Ausdehnung der Endometriosetumore. Der bisher verwendete rAFS-Score ist für eine klinisch relevante Einteilung der Erkrankung nicht geeignet, wie an einem eigenen Patientinnenkollektiv retrospektiv nachgewiesen werden konnte. Abstract The ENZIAN-Score is presented as a new instrument to classify the deep infiltrating endometriosis. Especially the retroperitoneal part of the severe endometriosis is focussed on. In analogy to an oncological staging four different stages are pronounced. The localisation and the expansion of the endometriosis nodule was indicated to different subgroups. The still used rAFS-score is of no clinical evidence, as we pointed out in a retrospective study of our patients with severe intestinal endometriosis. Schlüsselwörter tiefe Endometriose - ENZIAN-Score - rAFS-Score - laparoskopische Darmresektion Key words deep endometriosis - ENZIAN-Score - rAFS-Score - laparoscopic bowelresection Literatur - 1 Schultes G. Classification of endometriosis. Wien Med Wochenschr. 1999; 149 361-365 - 2 Keckstein J, Ulrich U, Kandolf O, Wiesinger H, Wustlich M. Die laparoskopische Therapie der Darmendometriose und der Stellenwert der medikamentösen Therapie. Zentralbl Gynäkol. 2003; 125 259-266 - 3 Keckstein J, Ulrich U, Possover M, Schweppe K W. ENZIAN-Klassifikation der tief infiltrierenden Endometriose. Zentralbl Gynäkol. 2003; 125 291 - 4 Porpora M G, Koninckx P R, Piazze J, Natili M, Colagrande S, Cosmi E V. Correlation between endometriosis and pelvic pain. J Am Assoc Gynecol Laparosc. 1999; 6 429-434 - 5 Guzick D S, Bross D S, Rock J. Assessing the efficacy of The American Fertility Society's classification of endometriosis: application of a dose-response methodology. Fertil Steril. 1982; 38 171-176 - 6 Wang H B, Lang J H, Leng J H, Liu Z F, Sun D W, Zhu L. Clinical study about diagnosis and management on 10 women with rectovaginal endometriosis. Zhonghua Fu Chan Ke Za Zhi. 2003; 38 277-279 - 7 Chapron C, Fauconnier A, Vieira M, Barakat H, Dousset B, Pansini V, Vacher-Lavenu M C, Dubuisson J B. Anatomical distribution of deeply infiltrating endometriosis: surgical implications and proposition for a classification. Hum Reprod. 2003; 18 157-161 F. Tuttlies LKH Villach Abt. für Gynäkologie und Geburtshilfe Nicolaigasse 43 A-9500 Villach Email: [email protected]

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Outcome instruments

Enzian

Condition tags

mesh:D004715endometriosisdie_deep_infiltrating

MeSH descriptors

Endometriosis Endometriosis Endometrial Neoplasms Endometrial Neoplasms Endometriosis Female Humans Neoplasm Staging

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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