Elagolix for Endometriosis-Associated Pain: A Narrative Review and Indian Expert Consensus

Sanjay Gupte; Ramanidevi T; K D Nayyar; PM Gopinath; Rooma Sinha; Jeyarani Kamaraj; Jayanthi Reddy; Mala Raj; Girija Wagh; Parag Biniwale; Sushma Deshmukh; Chaitanya Ganpule; Sachin Kulkarni; Shivani S Gour; Onkar C Swami; Kamal Kumar; Neeraj Kumar

doi:10.7759/cureus.119395

Elagolix for Endometriosis-Associated Pain: A Narrative Review and Indian Expert Consensus

Sanjay Gupte, Ramanidevi T, K D Nayyar, PM Gopinath, Rooma Sinha, Jeyarani Kamaraj, Jayanthi Reddy, Mala Raj, Girija Wagh, Parag Biniwale, Sushma Deshmukh, Chaitanya Ganpule, Sachin Kulkarni, Shivani S Gour, Onkar C Swami, Kamal Kumar, Neeraj Kumar

In: Cureus · 2026 · doi:10.7759/cureus.119395 · W7225736332

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References (48)

Blood biomarkers for the non-invasive diagnosis of endometriosis via openalex
Cost-effectiveness of elagolix versus leuprolide acetate for treating moderate-to-severe endometriosis pain in the USA via openalex
Current Evidence and Emerging Directions in Endometriosis Pharmacotherapy: A Systematic Review of Recent Advances via openalex
Developing symptom-based predictive models of endometriosis as a clinical screening tool: results from a multicenter study via openalex
Diagnostic accuracy of cancer antigen 125 for endometriosis: a systematic review and meta-analysis via openalex
Dienogest and the Risk of Endometriosis Recurrence Following Surgery: A Systematic Review and Meta-analysis via openalex
Efficacy of Elagolix and Relugolix for the Treatment of Pelvic Pain in Patients With Endometriosis: A Systematic Review via openalex
Elagolix: First Global Approval via openalex
Endometriosis and infertility: pathophysiology, treatment strategies, and reproductive outcomes via openalex
Endometriosis and inflammatory immune responses: Indian experience via openalex
Endometriosis: A Review via openalex
Estrogen-progestins and progestins for the management of endometriosis via openalex
GnRH agonists in the treatment of symptomatic endometriosis: a review via openalex
Gonadotropin-releasing hormone antagonists versus agonists for endometriosis: a systematic review and meta-analysis of randomized controlled trials via openalex
Gynecological uses of GnRH antagonists: review article via openalex
Imaging modalities for the non-invasive diagnosis of endometriosis via openalex
Impact of family history for endometriosis, migraine, depression and early menopause on endometriosis symptoms, localization and stage: A case control study via openalex
Linzagolix therapy versus a placebo in patients with endometriosis-associated pain: a prospective, randomized, double-blind, Phase 3 study (EDELWEISS 3) via openalex
Long acting progestogens versus combined oral contraceptive pill for preventing recurrence of endometriosis related pain: the PRE-EMPT pragmatic, parallel group, open label, randomised controlled trial via openalex
Long-term effect of elagolix on bone mineral density: results from two phase 3 extension studies in women with endometriosis-associated pain via openalex
Long-term hormonal treatment reduces repetitive surgery for endometriosis recurrence via openalex
Long-Term Outcomes of Elagolix in Women With Endometriosis: Results From Two Extension Studies via openalex
Long-term treatment for endometriosis with dienogest: efficacy, side effects and tolerability via openalex
Medical Management of Endometriosis via openalex
Medical Treatment for Endometriosis: Tolerability, Quality of Life and Adherence via openalex
Non-invasive imaging techniques for diagnosis of pelvic deep endometriosis and endometriosis classification systems: an International Consensus Statement via openalex
Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2) via openalex
Prevalence; Characteristics and Management of Endometriosis Amongst Infertile Women: A One Year Retrospective Study via openalex
Progestins in the symptomatic management of endometriosis: a meta-analysis on their effectiveness and safety via openalex
Recent Advances in Endometriosis Pathophysiology and Pharmacological Treatment via openalex
Risk factors for non-response and discontinuation of Dienogest in endometriosis patients: A cohort study via openalex
The impact of early diagnosis of endometriosis on quality of life via openalex
Transvaginal ultrasound and magnetic resonance imaging in detecting rectosigmoid deep infiltrating endometriosis: a comparative meta-analysis via openalex
Transvaginal Ultrasound in the Diagnosis and Assessment of Endometriosis-An Overview: How, Why, and When via openalex
Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist via openalex
Treatment of endometriosis-associated pain with linzagolix, an oral gonadotropin-releasing hormone-antagonist: a randomized clinical trial via openalex
Use of dienogest in endometriosis: a narrative literature review and expert commentary via openalex
W4403541320 via openalex
W4404527318 via openalex
W4405782485 via openalex
W4407029705 via openalex
W3139553455 via openalex
W3185797914 via openalex
W3207063998 via openalex
W2990363083 via openalex
W3088950237 via openalex
W4214754424 via openalex
W4400163864 via openalex

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[1] Blood biomarkers for the non-invasive diagnosis of endometriosis via openalex

[2] Cost-effectiveness of elagolix versus leuprolide acetate for treating moderate-to-severe endometriosis pain in the USA via openalex

[3] Current Evidence and Emerging Directions in Endometriosis Pharmacotherapy: A Systematic Review of Recent Advances via openalex

[4] Developing symptom-based predictive models of endometriosis as a clinical screening tool: results from a multicenter study via openalex

[5] Diagnostic accuracy of cancer antigen 125 for endometriosis: a systematic review and meta-analysis via openalex

[6] Dienogest and the Risk of Endometriosis Recurrence Following Surgery: A Systematic Review and Meta-analysis via openalex

[7] Efficacy of Elagolix and Relugolix for the Treatment of Pelvic Pain in Patients With Endometriosis: A Systematic Review via openalex

[8] Elagolix: First Global Approval via openalex

[9] Endometriosis and infertility: pathophysiology, treatment strategies, and reproductive outcomes via openalex

[10] Endometriosis and inflammatory immune responses: Indian experience via openalex

[11] Endometriosis: A Review via openalex

[12] Estrogen-progestins and progestins for the management of endometriosis via openalex

[13] GnRH agonists in the treatment of symptomatic endometriosis: a review via openalex

[14] Gonadotropin-releasing hormone antagonists versus agonists for endometriosis: a systematic review and meta-analysis of randomized controlled trials via openalex

[15] Gynecological uses of GnRH antagonists: review article via openalex

[16] Imaging modalities for the non-invasive diagnosis of endometriosis via openalex

[17] Impact of family history for endometriosis, migraine, depression and early menopause on endometriosis symptoms, localization and stage: A case control study via openalex

[18] Linzagolix therapy versus a placebo in patients with endometriosis-associated pain: a prospective, randomized, double-blind, Phase 3 study (EDELWEISS 3) via openalex

[19] Long acting progestogens versus combined oral contraceptive pill for preventing recurrence of endometriosis related pain: the PRE-EMPT pragmatic, parallel group, open label, randomised controlled trial via openalex

[20] Long-term effect of elagolix on bone mineral density: results from two phase 3 extension studies in women with endometriosis-associated pain via openalex

[21] Long-term hormonal treatment reduces repetitive surgery for endometriosis recurrence via openalex

[22] Long-Term Outcomes of Elagolix in Women With Endometriosis: Results From Two Extension Studies via openalex

[23] Long-term treatment for endometriosis with dienogest: efficacy, side effects and tolerability via openalex

[24] Medical Management of Endometriosis via openalex

[25] Medical Treatment for Endometriosis: Tolerability, Quality of Life and Adherence via openalex

[26] Non-invasive imaging techniques for diagnosis of pelvic deep endometriosis and endometriosis classification systems: an International Consensus Statement via openalex

[27] Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2) via openalex

[28] Prevalence; Characteristics and Management of Endometriosis Amongst Infertile Women: A One Year Retrospective Study via openalex

[29] Progestins in the symptomatic management of endometriosis: a meta-analysis on their effectiveness and safety via openalex

[30] Recent Advances in Endometriosis Pathophysiology and Pharmacological Treatment via openalex

[31] Risk factors for non-response and discontinuation of Dienogest in endometriosis patients: A cohort study via openalex

[32] The impact of early diagnosis of endometriosis on quality of life via openalex

[33] Transvaginal ultrasound and magnetic resonance imaging in detecting rectosigmoid deep infiltrating endometriosis: a comparative meta-analysis via openalex

[34] Transvaginal Ultrasound in the Diagnosis and Assessment of Endometriosis-An Overview: How, Why, and When via openalex

[35] Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist via openalex

[36] Treatment of endometriosis-associated pain with linzagolix, an oral gonadotropin-releasing hormone-antagonist: a randomized clinical trial via openalex

[37] Use of dienogest in endometriosis: a narrative literature review and expert commentary via openalex

[38] W4403541320 via openalex

[39] W4404527318 via openalex

[40] W4405782485 via openalex

[41] W4407029705 via openalex

[42] W3139553455 via openalex

[43] W3185797914 via openalex

[44] W3207063998 via openalex

[45] W2990363083 via openalex

[46] W3088950237 via openalex

[47] W4214754424 via openalex

[48] W4400163864 via openalex