Successful conservative treatment of catamenial pneumothorax with GnRH agonist

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A patient with recurrent catamenial pneumothorax and suspected pleural endometriosis was treated with a GnRH agonist for nine months and remained asymptomatic 12 months after stopping treatment.

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This paper reports a 34-year-old woman with recurrent catamenial pneumothorax in whom pleural endometriosis was suspected, supported by cytology from pleural fluid showing glandular cell clusters of probable endometrial origin. The patient was treated with a long-acting GnRH agonist (triptorelin, 3.75 mg monthly intramuscularly) for nine months. After discontinuing therapy, she remained asymptomatic with regular periods 12 months later. This paper relates to endometriosis because it presents a conservative GnRH-agonist treatment of catamenial pneumothorax with suspected pleural endometriosis and supports the diagnosis/management context for thoracic endometriosis.

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Abstract

A thirty four year old woman with recurrent catamenial pneumothorax is described. Pleural endometriosis was suspected and cytologic examination of fluid drained from the right pleural cavity showed glandular cell clusters of probable endometrial origin. The patient received a long-acting GnRH agonist (Triptorelin-Arvekap-Ipsen) 3.75 mg/month I.M. for nine months and remains asymptomatic with regular periods 12 months after discontinuing the treatment. Similar content being viewed by others

References

Burry KA, Patton PHE, Illingworth DR (1989) Metabolic changes during medical treatment of endometriosis: nafarelin acetate versus danazol. Am J Obstet Gynecol 160:1454–1461 Casey ML, Hemsell DL, MacDonald PC, Johnston JM (1980) NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity in the human endometrium. Prostaglandin 19:115–122 Dattola RK, Toffle RC, Lewis MJ (1990) Catamenial pneumothorax. J Reprod Med 35:734–736 Dotson RL, Peterson MC, Doucette RC, Quinton R, Rawson RY, Parker Jones K (1993) Medical therapy for recurring catamential pneumothorax following pleurodesis. Obstet Gynecol 82:656–658 Foster DC, Stern JL, Buscema J (1981) Pleuralandparenchymalendometriosis. ObstetGynecol 58:552–556 Henzl MR, Corson SL, Moghissi K, Buttram VC, Berquist C, Jacobson J (1988) Administration of nasal nafarelin as compared with oral danazol for endometriosis. N Engl J Med 31:485–489 Hibbard LT, Schumann WR, Goldstein GE (1981) Thoracic endometriosis: a review and report of two cases. Am J Obstet Gynecol 140:227–232 Johnson WM, Tyndal CM (1987) Pulmonary endometriosis: treatment with danazol. Obstet Gynecol 69:506–507 Karpel JP, Appel D, Merav A (1985) Pulmonary endometriosis. Lung 163:151–159 Lillington GA, Mitchell SP, Wood GA (1972) Catamenial pneumothorax. JAMA 219:1328–1332 Markham SM, Carpenter SE, Rock JA (1989) Extrapelvic endometriosis Obstet. Gynecol Clin North Am 16:123–146 Maurer ER, Schaal FA, Mendez FL (1958) Chronic recurring spontaneous pneumothorax due to endometriosis of the diaphragm. JAMA 168:2013–2024 Rosenberg SM, Riddick DH (1981) Successfull treatment of catamenial hemoptysis with danazol. Obstet Gynecol 57:130–131 Rossi NP, Goplerud LP (1974) Recurrent catamenial pneumothorax. Arch Surg 109:173–176 Slasky BS, Siewers RD, Lecky JW (1982) Catamenial pneumothorax: the roles of diaphragmatic defects and endometriosis. AJR 138:639–645 Suginami H, Hamada K, Yano K (1985) A case of endometriosis of the lung treated with danazol. Obstet Gynecol 66 [Suppl]:685–715 Author information Authors and Affiliations Additional information Correspondence to: D. Lolis (address see above) Rights and permissions About this article Cite this article Lolis, D., Adonakis, G., Kontostolis, E. et al. Successful conservative treatment of catamenial pneumothorax with GnRH agonist. Arch Gynecol Obstet 256, 163–166 (1995). https://doi.org/10.1007/BF01314646 Received: Accepted: Issue date: DOI: https://doi.org/10.1007/BF01314646

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Condition tags

mesh:D004715

MeSH descriptors

Luteolytic Agents Pneumothorax Triptorelin Pamoate Adult Endometriosis Endometriosis Endometriosis Female Humans Luteolytic Agents Pleural Diseases Pleural Diseases Pleural Diseases Pneumothorax Pneumothorax Recurrence Triptorelin Pamoate

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