Gynecologic and obstetric investigation

BACKGROUND/AIMS: To estimate the prevalence of diagnosed endometriosis (DE) in women in the United States and assess the associated symptomatic burden. METHODS: An online, cross-sectional survey of women aged 18-49 years was conducted from…

BACKGROUND: Endometriosis is a chronic inflammatory disease for which no accurate peripheral diagnostic marker is available. Many cytokines and chemokines have been found altered in the plasma and peritoneal fluid of women with endometriosi…

AIM: The study aimed to investigate the efficacy of a dopamine agonist, quinagolide, on experimentally induced endometriosis in a rat model. METHODS: Twenty female Wistar rats were used in this experiment. Endometriosis was surgically indu…

BACKGROUND/AIMS: Endometriosis is viewed first and foremost as an estrogen-dependent disease, featuring not only excessive estrogen production but also aberrant expression of estrogen receptors (ERs), particularly ERβ, that mediate the estr…

UNLABELLED: BACKGROUND/AIM STUDY QUESTION: Endometriosis is associated with a significant reduction in the quality of life and higher depression and anxiety rates. The Dutch Endometriosis Society (ES) was founded to increase the recognition…

BACKGROUND: Endometriosis is a polygenic and multifactorial disease. DNA damage plays a major role in mutagenesis, carcinogenesis and aging and is usually repaired by the action of several DNA repair enzymes. We investigated the association…

OBJECTIVE: To investigate dynamic changes in myometrial thickness during the third stage of labor. METHODS: Myometrial thickness was measured using ultrasound at one-minute time intervals during the third stage of labor in the mid-region o…

BACKGROUND: The aim of the study was to investigate the levels of perceived stress in a group of women with a long-term history of endometriosis in conjunction with surgical and/or medical treatments. METHODS: A clinical trial was conducte…

AIMS: To determine the prevalence of endometriosis in epithelial ovarian cancers (EOC) and the association among their histological subtypes and with endometrial carcinoma. METHODS: An observational cohort study performed in 192 patients o…

OBJECTIVE: Endometrial cells may aberrantly express molecules involved in invasion and migration, leading to endometriosis. The aim of this study was to investigate the expression of DJ-1 and phosphorylated mammalian target of rapamycin (p-…

BACKGROUND/AIMS: The revised American Society for Reproductive Medicine classification of endometriosis has a limited predictive value for pregnancy after surgery. A tool for predicting spontaneous pregnancy or pregnancy following assisted …

OBJECTIVE: To investigate whether and how human chorionic gonadotropin (HCG) treatment ameliorates endometriosis in an endometriotic rat model. METHODS: Twenty-four endometriosis rats were established and were randomly divided into four gr…

BACKGROUND: A uterine cyst occurring as an extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD) is extremely rare. CASE: A 46-year-old Japanese woman was referred with a large abdominal mass causing severe abdom…

AIM: To evaluate the effects of combined treatment approaches on endometriosis-associated infertility in different stages of endometriosis using laparoscopy, gonadotropin-releasing hormone (GnRH) agonist (GnRHa) therapy and in vitro fertili…

Background/Aims: To evaluate serum prolactin and CA-125 levels as biomarkers for the diagnosis of peritoneal endometriosis. Methods: &l

BACKGROUND: The purpose of this report is to describe ovarian paragonimiasis, a rare form of lung fluke infestation, mimicking ovarian cancer. CASE: A 47-year-old Thai woman presented with a pelvic mass. Imaging suggested ovarian cancer wi…

Uterine leiomyoma (UL) is an estrogen-responsive benign tumor in the female reproductive system and the main risk of hysterectomy for women. However, gene polymorphism of estrogen-metabolizing enzymes may lead to the different susceptibilit…

Endometriosis is influenced by both genetic and environmental factors. Genetic factors make up about half of the variation in endometriosis. Nevertheless, the genetics of endometriosis remains complex and in part unsolved, but recently, bas…

OBJECTIVE: To investigate the clinical features of patients in Japan with malignant transformation of ovarian endometrioma. PATIENTS: Thirty-three patients diagnosed with ovarian cancer presumably arising from endometrioma were recruited r…

BACKGROUND/AIMS: To analyze whether the presence of endometriosis per se is associated with inferior pregnancy rates in women undergoing in vitro fertilization (IVF). METHODS: Between July 2005 and November 2012, a total of 485 patients wi…

BACKGROUND/AIM: To evaluate a possible lateralization of antral follicle count (AFC) based on the finding that endometriosis, if present, is more commonly found in the left hemipelvis. METHODS: We evaluated the records of 6,617 baseline ul…

Dear SirThe recent report by Zhao and Hao [1] on pelvic inflammatory disease (PID) in China is very interesting. They concluded that 'PID is the main cause of tubal infertility, but the etiology of PID has changed from [female genital tuber…

AIMS: To estimate the recurrence rate of patients with endometrial polyps and to evaluate whether the recurrence can be correlated with the histopathologic features of the polyp. METHODS: Two hundred and eighty-two women with endometrial p…