Regional anesthesia and pain medicine

BACKGROUND: Identifying modifiable patient-related risk factors may guide interventions aimed at reducing prolonged postoperative opioid use. Obstructive sleep apnea (OSA) has been hypothesized as one such condition. However, the associatio…

BACKGROUND/IMPORTANCE: Chronic postsurgical pain (CPSP) is a significant, often debilitating outcome of surgery, impacting patients' quality of life and placing a substantial burden on healthcare systems worldwide. CPSP (pain persisting for…

Pain affects millions worldwide, posing significant challenges in diagnosis and treatment. Despite advances in understanding pain mechanisms, there remains a critical need for validated biomarkers to enhance diagnosis, prognostication, and p…

INTRODUCTION: Chronic pelvic pain syndrome is a complex multifactorial condition with an increasing prevalence probably due to a rising awareness. Chronic pelvic pain syndrome is pain in the pelvic area and often accompanied with complaints…

BACKGROUND AND OBJECTIVES: Many women with endometriosis continue to have pelvic pain despite optimal surgical and hormonal treatment; some also have palpable pelvic floor muscle spasm. We describe changes in pain, spasm, and disability aft…

Translational research has not yet elucidated whether alterations in central pain processes are related to peripheral inflammatory processes in chronic pain patients. We tested the hypothesis that the concentration of cytokines in the perit…

BACKGROUND AND OBJECTIVES: : The classical technique for blocking the superior hypogastric plexus (SHP) described by Plancarte sometimes renders the desired needle placement difficult. This article describes an alternative approach for bloc…