Biomedical journal

lab-animal 2026

Low-energy extracorporeal shock wave therapy is associated with reduced inflammation and fibrosis in an E2-induced rat model of endometriosis and remains effective under menopause-mimicking conditions

doi:10.1016/j.bj.2026.101024 ·PMID:42546843

BACKGROUND: Endometriosis is an estrogen-dependent inflammatory disorder marked by ectopic lesions, chronic pelvic inflammation, and frequent recurrence. Extracorporeal shock wave therapy (ESWT) is a non-invasive modality with anti-inflamma…

lab-animal 2025

Guizhi Fuling Wan ameliorates concanavalin A-induced autoimmune hepatitis in mice

doi:10.1016/j.bj.2024.100731 ·PMID:38677491

BACKGROUND: Autoimmune hepatitis (AIH) is an immune-mediated hepatic disease associated with intense complications. AIH is more common in females and needs effective drugs to treat. Guizhi Fuling Wan (GZFLW) is a traditional Chinese herbal …

2023

Developing and validating clinical features-based machine learning algorithms to predict influenza infection in influenza-like illness patients.

doi:10.1016/j.bj.2022.09.002 ·PMID:36150651

BackgroundSeasonal influenza poses a significant risk, and patients can benefit from early diagnosis and treatment. However, underdiagnosis and undertreatment remain widespread. We developed and compared clinical feature-based machine learn…

lab-animal 2023

Effects of Rosa damascena on reproductive improvement, metabolic parameters, liver function and insulin-like growth factor-1 gene expression in estradiol valerate induced polycystic ovarian syndrome in Wistar rats

doi:10.1016/j.bj.2022.05.003 ·PMID:35605922

BACKGROUND: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in reproductive-age women. The present study aimed to evaluate the effects of Rosa damascena (RD) extract in estradiol valerate (EV) induced polycyst…

lab-animal 2022

epg5 knockout leads to the impairment of reproductive success and courtship behaviour in a zebrafish model of autophagy-related diseases.

doi:10.1016/j.bj.2021.04.002 ·PMID:35562284

BackgroundDysregulation of the autophagic flux is linked to a wide array of human diseases, and recent findings highlighted the central role of autophagy in reproduction, as well as an association between impairment of autophagy and behavio…

observational 2022

Hysteroscopic cervical features associated with difficult embryo transfer in unselected patients undergoing in vitro fertilization

doi:10.1016/j.bj.2021.06.009 ·PMID:34237454

BACKGROUND: The most appropriate diagnostic tests for the assessment of the uterine cavity in patients undergoing standard infertility evaluation in daily practice remain unclear. Routine hysteroscopic uterine cavity evaluation before an in…

observational 2017

Bilaterality of ovarian endometriomas does not affect the outcome of in vitro fertilization/intracytoplasmic sperm injection in infertile women after laparoscopic cystectomy

doi:10.1016/j.bj.2017.06.009 ·PMID:29179885

BACKGROUND: To assess whether the unilateral or bilateral lesions can affect ovarian reserve and pregnancy outcome in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) in infertility patients underwent laparoscopic cystecto…

other 2017

Oxidative stress and diabetes: Glucose response in the cROSsfire

doi:10.1016/j.bj.2017.10.001 ·PMID:29179878

In this issue of the Biomedical Journal, we discuss the emerging role of reactive oxygen species (ROS) in the development of insulin resistance and ultimately type 2 diabetes. We focus also on research investigating the outcome of in vitro …

rct 2015

Inferior hypogastric plexus blockade versus acupuncture for the management of idiopathic chronic pelvic pain: A randomized clinical trial

doi:10.4103/2319-4170.151034 ·PMID:25673173

BACKGROUND: To compare the clinical efficacies of inferior hypogastric plexus blockade and acupuncture in the management of idiopathic chronic pelvic pain (CPP). METHODS: The study included 117 patients with CPP. Group 1 included 62 patien…