Endometriosis is a chronic inflammatory disease with cancer-like features, yet the mechanisms linking metabolic dysregulation to immune remodeling during lesion progression remain poorly understood. Here, we identify the ubiquitin E3 ligase…
Introduction: Pulmonary endometriosis (PE) is an unusual cause of catamenial hemoptysis, with only a small proportion of endometriosis cases involving the thorax. Standard management often involves surgical resection combined with hormonal …
Introduction: Pulmonary endometriosis (PE) is an unusual cause of catamenial hemoptysis, with only a small proportion of endometriosis cases involving the thorax. Standard management often involves surgical resection combined with hormonal …
The rapid advances in epigenetic and epitranscriptomic regulatory mechanisms have opened new prospects for precision therapies in various diseases. N-acetyltransferase 10 (NAT10) is currently the only known eukaryotic RNA ac4C acetyltransfe…
BACKGROUND: Embryos derived from in vitro fertilization (IVF) single pronucleus (1PN) zygotes can achieve live births. The pronucleus size of 1PN zygotes is related to their embryonic development potential. However, these studies cannot dra…
OBJECTIVE: To investigate the association between ultrasonographic features of ovarian endometrioma (OMA) and diminished ovarian reserve, and to evaluate the predictive value of these ultrasound markers. METHODS: This prospective observati…
BACKGROUND: A link exists between decorin (DCN) and endometriosis, nevertheless, the role of DCN in this condition remains unclear. This study aims to bioinformatically characterize DCN expression, diagnostic value, and related signaling in…
ObjectiveTo evaluate whether vitamin D supplementation improves live birth rates in women with polycystic ovary syndrome undergoing in vitro fertilisation.DesignMulticentre, double blind, placebo controlled, randomised clinical trial.Settin…
Following the initial treatment of nasopharyngeal carcinoma (NPC), tumor progression often portends an adverse prognosis for these patients. MicroRNAs (miRNAs) have emerged as critical regulators of tumor immunity, yet their intricate mecha…
Adenomyosis is characterized by the invasion of endometrial glands and stroma into the myometrium. Its clinical manifestations often include dysmenorrhoea, excessive menstrual bleeding and infertility. Reduced pregnancy and live birth rates…
Endometriosis with ovarian cysts is common in reproductive-age women and contributes to pain and infertility. The influence of age on clinical and surgical outcomes remains uncertain. This retrospective study analyzed 994 patients diagnosed…
BACKGROUND: There is limited research about the pregnancy outcomes of POSEIDON group 2 patients. This study aims to evaluate the factors related to the clinical outcomes of in vitro fertilization (IVF) and/or intracytoplasmic sperm injectio…
BACKGROUND: To discover the related factors of ovarian reserve function and explore the relationship between AFC and AMH. METHODS: In this study, a retrospective analysis of endometriosis cases from January 2022 to December 2023 was perfor…
Endometritis is a common reproductive disorder in dairy cows, with antibiotics being the primary treatment option. However, the overuse of antibiotics has contributed to the growing problem of antimicrobial resistance. Antimicrobial peptide…
BACKGROUND: Threatened abortion is a common obstetric complication where early risk stratification is crucial for clinical management. CA125, a glycoprotein biomarker produced by endometrial and trophoblastic tissues, may serve as a valuabl…
This study aimed to investigate the associations between a dietary index for gut microbiota (DI-GM), flavonoid intake, and female infertility, while exploring age-specific differences in these relationships to identify potential dietary str…
Nonsugar sweeteners (NSSs) are added to foods and beverages to provide sweetness in place of sugar while reducing the total caloric content. Reducing sugar intake, and corresponding calories, may decrease the risk of diabetes and other heal…
UNLABELLED: A good quality egg is essential for a successful pregnancy and early embryo development. Oocyte development is vulnerable to environmental exposures. Bisphenol S (BPS) is widely used as a replacement for its analog bisphenol A, …
This article reports the clinical diagnosis and treatment of a 42-year-old female patient with a giant cervical leiomyoma, a rare condition. A review of the literature over the past 30 years reveals only one reported case of a cervical inte…
BACKGROUND: Myofascial pelvic pain syndrome (MPPS) is a common but often underdiagnosed cause of chronic pelvic pain in women, significantly affecting quality of life. Early and accurate identification of patients at risk is essential for i…
The Levonorgestrel-releasing Intrauterine System (LNG-IUS) is extensively utilized in the treatment of adenomyosis. However, the displacement and expulsion of the LNG-IUS bring significant challenges. This was a retrospective analysis compa…
BACKGROUND: Female infertility is a global health issue, with metabolic disorders emerging as significant contributors. Liver steatosis, characterized by excessive hepatic fat accumulation, is closely linked to metabolic dysfunction and may…
Reduced lymphoid enhancer-binding factor 1 (LEF1) expression in patients with adenomyosis during the mid-secretory phase leads to impaired endometrial receptivity, affecting embryo implantation. This study investigated the molecular mechani…