Brenda Eskenazi

ORCID: 0000-0001-7609-6852 · 20 papers in corpus
observational 2025
International journal of hygiene and environmental health ·doi:10.1016/j.ijheh.2025.114612

Phthalates, parabens, and other phenols are present in consumer products humans use every day, including personal care products and food packaging. Exposure to these chemicals may have endocrine disrupting effects. The menstrual cycle is gu…

observational 2021
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deaa324

STUDY QUESTION: Is there an association between 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure and fecundability and infertility among Seveso women and their daughters? SUMMARY ANSWER: TCDD exposure is associated with a decrease in fe…

other 2019
Environmental health perspectives ·doi:10.1289/ehp4971

BACKGROUND: Identification of female reproductive toxicants is currently based largely on integrated epidemiological and in vivo toxicology data and, to a lesser degree, on mechanistic data. A uniform approach to systematically search, orga…

observational 2018
International journal of epidemiology ·doi:10.1093/ije/dyy165

BACKGROUND: 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) is proposed to interfere with fetal growth via altered activity of the aryl hydrocarbon receptor (protein: AHR; gene: AHR) pathway which regulates diverse biological and developmenta…

review 2018
Environment international ·doi:10.1016/j.envint.2018.08.051

A 1976 chemical factory explosion near Seveso, Italy exposed residents to high levels of 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD or dioxin). Dioxin is a known human carcinogen and potent endocrine disruptor. It is highly lipophilic and h…

observational 2013

Dioxin, a ubiquitous contaminant of industrial combustion processes including medical waste incineration, has been implicated in the etiology of endometriosis in animals. We sought to determine whether dioxin exposure is associated with end…

observational 2011
Environmental health perspectives ·doi:10.1289/ehp.1103720

BACKGROUND: 2,3,7,8-Tetrachlorodibenzo-para-dioxin (TCDD), a widespread environmental contaminant, disrupts multiple endocrine pathways. The International Agency for Research on Cancer classified TCDD as a known human carcinogen, based on p…

meta-analysis 2010
Human Reproduction Update ·doi:10.1093/humupd/dmq042

BACKGROUND: Combined oral contraceptives (OCs) inhibit ovulation, substantially reduce the volume of menstrual flow and may hypothetically interfere with implantation of refluxed endometrial cells. The aim of this review is to establish if …

other 2010
Epidemiology (Cambridge, Mass.) ·doi:10.1097/ede.0b013e3181cb8b95

BACKGROUND: Pollution may play a role in population trends of declining semen quality and regional differences in time to pregnancy (TTP) in industrialized societies. Dioxins including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) have been su…

observational 2004
Environmental health perspectives ·doi:10.1289/ehp.6573

In 1976, a chemical plant explosion near Seveso, Italy, resulted in the highest known exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in residential populations. In 1996, we initiated the Seveso Women's Health Study (SWHS), a histori…

other 2004
Environmental health perspectives ·doi:10.1289/ehp.7004

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a widespread environmental contaminant, is associated with delays in pubertal development in animal studies. On 10 July 1976, as a result of a chemical explosion, residents of Seveso, Italy, exper…

other 2003
Environmental health perspectives ·doi:10.1289/ehp.5800

In this article we consider the importance of assessing endocrine disruption in a large new cohort that has been proposed, the National Children's Study (NCS). We briefly review evidence that endocrine disruption is a potentially important …

other 2002
Environmental health perspectives ·doi:10.1289/ehp.110-a559
observational 2002
Environmental health perspectives ·doi:10.1289/ehp.02110625

2,3,7,8-Tetrachlorodibenzo-(italic)p(/italic)-dioxin (TCDD or dioxin), a widespread environmental contaminant, has been shown to disrupt multiple endocrine pathways. The International Agency for Research on Cancer classified TCDD as a known…

observational 2002
Environmental health perspectives ·doi:10.1289/ehp.02110629

Dioxin, a ubiquitous contaminant of industrial combustion processes including medical waste incineration, has been implicated in the etiology of endometriosis in animals. We sought to determine whether dioxin exposure is associated with end…

2002
diagnostic-accuracy 2001
Fertility and sterility ·doi:10.1016/s0015-0282(01)02736-4

OBJECTIVE: To determine whether the surgical diagnosis of endometriosis can be predicted using symptoms, signs, and ultrasound findings. DESIGN: Prospective study (study sample); retrospective record review (test sample). SETTING: Hospita…

review 1997
Obstetrics and Gynecology Clinics of North America ·doi:10.1016/s0889-8545(05)70302-8

This article summarizes present knowledge about the epidemiology of endometriosis. Surprisingly, little is known about the prevalence or risk factors of endometriosis, given the medical care and employment costs. Knowledge about the epidemi…

other 1994
Environmental health perspectives ·doi:10.1289/ehp.94102476

A recent study by Rier et al. showed that rhesus monkeys exposed daily for 4 years to 5 or 25 ppt of dioxin in food develop endometriosis, with incidence and severity related to dose. We aimed to determine whether the total time-integrated …

1994
·doi:10.2307/3432044

A recent study by Rier et al. showed that rhesus monkeys exposed daily for 4 years to 5 or 25 ppt of dioxin in food develop endometriosis, with incidence and severity related to dose. We aimed to determine whether the total time-integrated …