Wiryawan Permadi

OBJECTIVE: Endometriosis is a chronic gynecological disease associated with inflammation and severe pelvic pain in 6%-10% of women of reproductive age. Although the pathophysiology and management of endometriosis are currently understood, f…

Endometriosis is an enigmatic disease affecting approximately 10% of the population. This unique disease is often chronic and characterized by inflammation. Even though endometriosis and its related disease, adenomyosis, are benign tumors, …

Aims: To explore early symptoms and lived experiences of endometriosis during adolescence, as recalled by adult women diagnosed with endometriosis, to identify indicators for a screening questionnaire for high school girls.Background: Endom…

Background: Endometriosis involves the presence of endometrial-like tissue outside the uterus, driven by inflammatory pathways including elevated interleukin-32 and vascular endothelial growth factor. One potential anti-inflammatory agent i…

Background: Endometriosis is a chronic gynecological disorder characterized by the presence of endometriosis-like tissue outside the uterine cavity, leading to pelvic pain, infertility, and other reproductive complications. Emerging evidenc…

OBJECTIVE: This study aimed to investigate the levels of chitinase-3-like protein-1 (CHI3L1), matrix metalloproteinase-9 (MMP-9), and monocyte chemoattractant protein-1 (MCP-1) in adenomyosis, as compared to normal myometrial tissue. These …

Background: Low birth weight (LBW) is a risk factor associated with endometriosis. Our study aimed to analyze the risk of endometriosis in women with a LBW history and the relationships of progesterone receptor B (PR-B) gene promoter methyl…

Objectives: This study aimed to examine the effect of a laparoscopic cystectomy on ovarian reserve assessed by measuring the levels of serum follicle stimulating hormone (FSH) and anti-Müllerian hormone (AMH). Materials and Methods: This pr…

Endometriosis has a major impact on women’s quality of life. The two primary pathologies are chronic inflammation and altered apoptotic activity. Sulawesi propolis has been shown to have known anti-inflammatory and pro-apoptotic properties …

Adenomyosis is a pathological condition characterized by the presence of endometrial glands and stroma within the myometrium. Endometrial like cells development was influenced by local inflammatory reactions, increases local estradiol due t…

Background: The correlation between endometrioma and serum Anti-mullerian hormone (AMH) level is a benchmark in determining the prognosis and management of endometrioma. Endometrioma causes a decrease in ovarian reserve due to tissue damage…

Objectives: This study aimed to measure the vascular endothelial growth factor (VEGF) expression in menstrual effluent from patients with endometriosis compared to non-endometriosis through immunocytochemical methods. We also measured the d…

Endometriosis is a gynecological disease characterized by the presence of endometrial-like tissue outside the uterine cavity. Remodeling of the extracellular matrix (ECM) is a prerequisite for tissue implantation. The presence of matrix met…

Background: Endometriosis is a progressive chronic gynecological disease. There are indications that endometriosis patients have lower progesterone receptor B (PR-B) levels. Menstrual blood contains the same mRNA derived from endometrium ce…

Aim: To identify the correlation between mRNA expression of aromatase, 17β-HSD2 level of TGF-β1 and stage of endometriosis. Methods: Case control study was done on 80 patients divided by 40 endometriosis patients and 40 patients as control.…