Jianzhang Wang

ORCID: 0000-0001-5931-9356 · 48 papers in corpus · active 2019-2026

Study types

  • article 29
  • dataset 10
  • preprint 4
  • other 3
  • review 2

Condition tags

  • endometriosis 37
  • mesh:D004715 17
  • adenomyosis 14
  • dysmenorrhea 4
  • infertility 3
  • endometrioma 2
  • mesh:D004412 2
  • bowel_endometriosis 1
  • die_deep_infiltrating 1
  • chronic_pelvic_pain 1
other 2026
iScience ·doi:10.1016/j.isci.2026.115678

Endometriosis, a prevalent gynecological disease affecting women's health, involves altered immune function. This study investigates the immune checkpoint protein, V-domain immunoglobulin suppressor of T cell activation (VISTA) as a therape…

article 2025
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2025.104796
article 2025
Science China. Life sciences ·doi:10.1007/s11427-025-2981-1
article 2025
Annals of medicine ·doi:10.1080/07853890.2025.2534521

BACKGROUND: Extrinsic adenomyosis exhibits heterogeneous clinical symptoms, with pain being more commonly reported. The relationship between magnetic resonance imaging (MRI) feature and symptom remains unclear. OBJECTIVE: To evaluate the pe…

other 2025
Scientific reports ·doi:10.1038/s41598-024-84608-5

This study aimed to elucidate the role of microRNA-92a-3p (miR-92a-3p) in the pathogenesis of adenomyosis. We examined how miR-92a-3p, found in exosomes derived from ectopic lesions, influences the behaviour of endometrial cells, dorsal roo…

article 2025
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202501493r

The studies on how mast cells mediate endometriosis pain are still limited. Mas-related G protein-coupled receptor member X2 (MRGPRX2), a receptor expressed on mast cells, participates in pain, inflammation, and itch. However, it is still u…

review 2025
International journal of biological sciences ·doi:10.7150/ijbs.116635

Endometriosis is a prevalent gynaecological disorder characterized by estrogen-dependent lesions. Pain-particularly dysmenorrhea, chronic pelvic pain, and dyspareunia-is the hallmark symptom of endometriosis. While pain mechanisms remain po…

article 2024
European journal of histochemistry : EJH ·doi:10.4081/ejh.2024.4052

Endometriosis is an estrogen-dependent inflammatory gynecological disease whose pathogenesis is unclear. C-C motif chemokine ligand 18 (CCL18), a chemokine, is involved in several inflammatory diseases. In this study, we aimed to investigat…

other 2024
Protein & cell ·doi:10.1093/procel/pwae012

Adenomyosis is a poorly understood gynecological disorder lacking effective treatments. Controversy persists regarding "invagination" and "metaplasia" theories. The endometrial-myometrial junction (EMJ) connects the endometrium and myometri…

preprint 2024
·doi:10.21203/rs.3.rs-3961335/v1
article 2024
International journal of biological macromolecules ·doi:10.1016/j.ijbiomac.2024.136318

Aberrantly expressed circRNAs affects various anti-tumour immune responses and immune cell regulation. However, the exact function of circGLIS2 on the pathogenesis of EMs remains unclear. In this study, we found that circGLIS2 was upregulat…

article 2024
·doi:10.31083/j.ceog5101014

Background: The adverse perinatal outcome caused by adenomyosis has been widely concerned recently, but little attention has been paid to whether the positional relationship between placenta and adenomyotic lesion influences the maternal an…

preprint 2023
·doi:10.21203/rs.3.rs-3194957/v1

Abstract Purpose Although adenomyosis is a common and benign gynecological disease, the specific pathogenesis of this condition has yet to be fully elucidated. It is difficult to culture primary cells of the ectopic endometrial epithelia an…

article 2023
Archives of gynecology and obstetrics ·doi:10.1007/s00404-023-07254-8
article 2023
JAMA network open ·doi:10.1001/jamanetworkopen.2023.17860

Importance: Adenomyosis is a common chronic gynecological disorder, and its treatment is an unmet need. New therapies need to be developed. Mifepristone is being tested for adenomyosis treatment. Objective: To determine whether mifepristone…

article 2023
Frontiers in immunology ·doi:10.3389/fimmu.2023.1106771

Pain is one of the main clinical symptoms of endometriosis, but its underlying mechanism is still not clear. Recent studies have shown that the secretory mediators of mast cells activated by estrogen are involved in the pathogenesis of endo…

article 2023
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-023-01371-0
article 2023
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2023.112040

Lack of sensitive biomarkers in the early stages of endometriosis (EMs) results in delayed diagnosis and intervention. Long non-coding RNAs (lncRNAs) have prognostic and diagnostic values in various diseases. However, the prognostic and dia…

dataset 2022
·doi:10.6084/m9.figshare.20408677

Additional file 1. Clinical characteristics of endometriosis and control patients in this study.

review 2022
International journal of biological sciences ·doi:10.7150/ijbs.72707

Endometriosis remains a common but challenging gynecological disease among reproductive-aged women with an unclear pathogenesis and limited therapeutic options. Numerous pieces of evidence suggest that NF-κB signaling, a major regulator of …

article 2022
Frontiers in genetics ·doi:10.3389/fgene.2022.828238

Although long non coding RNAs (lncRNAs) and circular RNAs (circRNAs) play important roles in the pathogenesis of diseases, endometriosis related lncRNAs and circRNAs are still rarely reported. This study focused on the potential molecular m…

article 2022
Frontiers in medicine ·doi:10.3389/fmed.2021.815628

Objective: To determine whether endometrioma recurrence is closely related to the presence of extrinsic adenomyosis, which was demonstrated by magnetic resonance imaging (MRI). Design: Observational crosssectional study involving patients w…

article 2022
Frontiers in surgery ·doi:10.3389/fsurg.2022.914661

Objective: This study aims to evaluate the factors associated with complications and long-term results in the surgical treatment of intestinal deep endometriosis and to figure out the optimized treatment measures for bowel endometriosis. Me…

article 2022
Journal of ovarian research ·doi:10.1186/s13048-022-01018-9

BACKGROUND: Many factors can affect the recurrence of endometriosis after surgery, however, whether endometriotic cyst fluid contributes to endometriosis recurrence after surgical excision of ovarian endometriomas remains unclear. The objec…

dataset 2021
·doi:10.6084/m9.figshare.14684629

Additional file 10: Table S9. List of differential genes in subtypes of mast cells.