Nicholas A Leyland

No ORCID on file · 10 papers in corpus · active 2005-2022

Study types

  • article 6
  • other 4

Condition tags

  • endometriosis 7
  • mesh:D004715 5
  • chronic_pelvic_pain 3
  • mesh:D017699 3
  • mesh:D004412 1
article 2022
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC ·doi:10.1016/j.jogc.2022.11.003
article 2021
Scientific reports ·doi:10.1038/s41598-021-98380-3

Endometriosis is a chronic, estrogen-dependent gynecological condition affecting approximately 10% of reproductive age women. The most widely accepted theory of its etiology includes retrograde menstruation. Recent reports suggest the uteru…

other 2021
Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2021.01.010

STUDY OBJECTIVE: The objective of our study was to provide a contemporary description of hysterectomy practice and temporal trends in Canada. DESIGN: A national whole-population retrospective analysis of data from the Canadian Institute fo…

other 2018
Biology of reproduction ·doi:10.1093/biolre/ioy019

MicroRNA (miRNA), noncoding segments of RNA involved in post-transcriptional regulation of protein expression are differentially expressed in eutopic endometrium of women with and without endometriosis compared to endometriotic lesions. How…

article 2018
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC ·doi:10.1016/j.jogc.2018.08.015
article 2018
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC ·doi:10.1016/j.jogc.2018.08.017
article 2015
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.09.003

OBJECTIVE: To evaluate novel clinical markers of endometriosis including the neurotrophins brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and neurotrophin 4/5 (NT4/5) and compare them to others previously reported in t…

other 2015
Human Reproduction ·doi:10.1093/humrep/dev018

STUDY QUESTION: Are brain-derived neurotrophic factor (BDNF) and its receptors, NTRK2, NGFR and SORT1, regulated by ovarian steroids in the uterus? SUMMARY ANSWER: BDNF and its low affinity receptor, nerve growth factor receptor (NGFR), ar…

article 2008
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC ·doi:10.1016/s1701-2163(16)32879-1
other 2005
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC ·doi:10.1016/s1701-2163(16)30993-8

OBJECTIVE: To improve the understanding of chronic pelvic pain (CPP) and to provide evidence-based guidelines of value to primary care health professionals, general obstetricians and gynaecologists, and those who specialize in chronic pain.…