John Aplin

ORCID: 0000-0001-8777-9261 · 10 papers in corpus
other 2026
Nature immunology ·doi:10.1038/s41590-026-02651-y

Inflammation occurs during the recurring cycles of tissue degradation, repair and remodeling in the uterus, but the mechanisms by which the immune system contributes to uterine tissue integrity are unclear. We reveal that uterine monocytes …

other 2023
Reproduction & fertility ·doi:10.1530/RAF-22-0115

Genome-wide analysis of gene expression has been widely applied to study the endometrium, although to our knowledge no systematic reviews have been performed. Here, we identified 74 studies that described transcriptomes from whole (unproces…

2015
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ·doi:10.3410/f.718530552.793503782
2014
·doi:10.3410/f.718502125.793498562
observational 2011

In order for embryo implantation to occur, there must be synchronisation between the development of the blastocyst and the differentiating endometrium, which is refractory to implantation for all but about four days of the menstrual cycle. …

observational 2010
Human Reproduction ·doi:10.1093/humrep/dep401

BACKGROUND: Endometriosis is a common cause of infertility and pelvic pain. Lectin histochemistry has shown that glycan expression is a sensitive marker of differentiation in the normal endometrium. Endometrial biopsies were taken during th…

2010
·doi:10.3410/f.5812956.5794054
review 2009
Journal of anatomy ·doi:10.1111/j.1469-7580.2008.01034.x

Cell adhesion in endometrial epithelium is regulated to maintain the continuity and protectiveness of the luminal covering cell layer while permitting interstitial implantation of the embryo during a restricted period of about 4 days. Many …

other 2009
Human Reproduction ·doi:10.1093/humrep/dep233

BACKGROUND: Ectopic pregnancy is a major cause of maternal morbidity and mortality with increasing incidence worldwide. We have investigated whether epithelia from Fallopian tubes (FTs) bearing an ectopic pregnancy differ from normal tubes …

review 1997
Biochemical Society transactions ·doi:10.1042/bst0251184

Conference Article| November 01 1997 Progesterone regulates glycosylation in endometrium J. D. Aplin; J. D. Aplin 1 *Department of Obstetrics and Gynaecology, University of Manchester, St Mary's Hospital, Manchester M13 0JH, U.K. 1To whom c…