Young Sang Oh

No ORCID on file · 12 papers in corpus · active 2013-2022

Study types

  • article 11
  • other 1

Condition tags

  • endometriosis 10
  • mesh:D004715 7
  • endometrioma 3
  • adenomyosis 2
article 2022
Dienogest May Reduce Estradiol- and Inflammatory Cytokine-Induced Cell Viability and Proliferation and Inhibit the Pathogenesis of Endometriosis: A Cell Culture- and Mouse Model-Based Study
Biomedicines ·doi:10.3390/biomedicines10112992

Dienogest (DNG) is a therapeutic medication used in endometriosis treatment. Limited data are available regarding its mechanism of action on endometrial cells. Using in vivo and in vitro models, we investigated whether DNG treatment causes …

article 2021
Increased Expression of Retinol-Binding Protein 4 in Ovarian Endometrioma and Its Possible Role in the Pathogenesis of Endometriosis
International journal of molecular sciences ·doi:10.3390/ijms22115827

Although endometriosis is a benign disease characterized by the presence of endometrial tissues outside the uterus, ectopic endometrial cells can exhibit malignant biological behaviors. Retinol-binding protein4 (RBP4) is a novel adipocyte-d…

article 2019
Effects of dienogest on breast : MCF cell line data
·doi:10.1016/j.fertnstert.2019.07.926
other 2019
Elevated serum interleukin-32 levels in patients with endometriosis: A cross-sectional study
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13149

PROBLEM: Recently, interleukin (IL)-32 has been suggested to be involved in the pathogenesis of endometriosis. The aim of this study was to investigate whether serum IL-32 level might be used as a biomarker for diagnosis of endometriosis. …

article 2019
Elevated serum interleukin-32 levels in patients with endometriosis: a prospective case-control study
·doi:10.1016/j.fertnstert.2019.07.931
article 2018
Role of interleukin-32 in the pathogenesis of endometriosis: in vitro, human and transgenic mouse data
Human Reproduction ·doi:10.1093/humrep/dey055

STUDY QUESTION: Does interleukin-32 (IL-32) play a role in the pathogenesis of endometriosis? SUMMARY ANSWER: IL-32 might be involved in the pathogenesis of endometriosis through increased viability, proliferation and invasion of endometria…

article 2016
Decreased Progesterone Receptor B/A Ratio in Endometrial Cells by Tumor Necrosis Factor-Alpha and Peritoneal Fluid from Patients with Endometriosis
Yonsei medical journal ·doi:10.3349/ymj.2016.57.6.1468

PURPOSE: Progesterone resistance is thought to be a major factor that contributes to progression of endometriosis. However, it is not clear what causes progesterone resistance in endometriosis. This study aimed to assess whether cytokines o…

article 2016
Increased expression of nuclear factor kappa-B p65 subunit in adenomyosis
Obstetrics & gynecology science ·doi:10.5468/ogs.2016.59.2.123

OBJECTIVE: Nuclear factor kappa-B (NF-κB) is a critical proinflammatory regulator that has been suggested to play a pivotal role in the pathogenesis and pathophysiology of endometriosis. In the present study, we aimed to evaluate whether th…

article 2015
Increased expression of p21-activated kinase 4 in adenomyosis and its regulation of matrix metalloproteinase-2 and -9 in endometrial cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.12.124
article 2015
Possible Role of Phthalate in the Pathogenesis of Endometriosis: In Vitro, Animal, and Human Data
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2015-2478

CONTEXT: Although phthalates were shown to have several negative effects on reproductive function in animals, its role in the pathogenesis of endometriosis remains to be elucidated. OBJECTIVE: We aimed to investigate the in vitro and in viv…

article 2013
Increased Nuclear Expression of Nuclear Factor Kappa‐B p65 Subunit in the Eutopic Endometrium and Ovarian Endometrioma of Women with Advanced Stage Endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12161

PROBLEM: We evaluated whether the expression of NF-кB p65 subunit is increased in the eutopic endometrium and/or in the ovarian endometrioma of women with advanced stage endometriosis, and ascertained in vitro effects of proinflammatory cyt…

article 2013
Regulation of P21-Activated Kinase-4 by Progesterone and Tumor Necrosis Factor-α in Human Endometrium and Its Increased Expression in Advanced-Stage Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2012-2969

CONTEXT: Endometriosis is a common gynecological condition characterized by enhanced proliferation, adhesiveness, invasiveness, and survival of endometrial cells after retrograde menstruation. Originally identified as a cytoskeletal regulat…