Parameswaran Grace Luther Lalitkumar

No ORCID on file · 5 papers in corpus · active 2018-2024

Study types

  • other 3
  • article 2

Condition tags

  • mesh:D004715 4
  • endometriosis 4
  • endometrioma 2
  • chronic_pelvic_pain 1
  • infertility 1
  • adenomyosis 1
other 2024
Communications biology ·doi:10.1038/s42003-024-06713-5

Current therapeutics of endometriosis focus on hormonal disruption of endometriotic lesions (ectopic endometrium, EcE). Recent findings show higher glycolysis utilization in EcE, suggesting non-hormonal strategy for disease treatment that a…

other 2024
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1465393

BACKGROUND: Endometriosis is characterized by the ectopic growth of endometrial-like cells, causing chronic pelvic pain, adhesions and impaired fertility in women of reproductive age. Usually, these lesions grow in the peritoneal cavity in …

article 2023
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1026168

Objective Bromocriptine treatment has been shown to reduce menstrual bleeding and pain in women with adenomyosis in a pilot clinical trial. The underlying mechanism contributing to the treatment effect is however unknown. The purpose of thi…

article 2020
Human Reproduction ·doi:10.1093/humrep/deaa164

STUDY QUESTION: What is the physiological role of transforming growth factor-beta (TGF-β1) and syndecans (SDC1, SDC4) in endometriotic cells in women with endometriosis? SUMMARY ANSWER: We observed an abnormal, pro-invasive phenotype in a s…

other 2018
Human Reproduction ·doi:10.1093/humrep/dey241

STUDY QUESTION: Is there molecular evidence for a link between endometriosis and endometriosis-associated ovarian cancers (EAOC)? STUDY ANSWER: We identified aberrant gene expression signatures associated with malignant transformation in a…