Ruan, Jingyao

Additional file 1: Figure 1. Succinate and SDHB expression in EMs milieu. (A) Succinate accumulation in PF of patients with EMs was confirmed by ELISA. (B) SDHB expression in normal endometrium (n = 5), and ectopic lesion (n = 3) by immunoh…

Additional file 1: Figure 1. Succinate and SDHB expression in EMs milieu. (A) Succinate accumulation in PF of patients with EMs was confirmed by ELISA. (B) SDHB expression in normal endometrium (n = 5), and ectopic lesion (n = 3) by immunoh…

Additional file 1.

Additional file 1.

Additional file 2.

Additional file 2.

Additional file 3.

Additional file 3.

Additional file 4.

Additional file 4.

Additional file 5: Supplementary Figure 1. Establishment of a Non-lethal Oxidative Stress Model in vitro. A Expression of 4-HNE is in endometrium and ectopic lesions (Scale bars, 20 μm) B-C: Cell viability (B) and fluorescence density (C) o…

Additional file 5: Supplementary Figure 1. Establishment of a Non-lethal Oxidative Stress Model in vitro. A Expression of 4-HNE is in endometrium and ectopic lesions (Scale bars, 20 μm) B-C: Cell viability (B) and fluorescence density (C) o…

Additional file 6: Supplementary Figure 2. Immunohistochemical staining of ST2, Vimentin, and E-cadherin. A Percentage of collagen area to total area in eutopic endometrium and ectopic lesion from controls and EMs patients as determined by …

Additional file 6: Supplementary Figure 2. Immunohistochemical staining of ST2, Vimentin, and E-cadherin. A Percentage of collagen area to total area in eutopic endometrium and ectopic lesion from controls and EMs patients as determined by …

Additional file 7: Supplementary Figure 3. Autocrine Effect of IL-33 on Stromal Cells. A-C. mRNA (A) and protein (B, C) expression of α-SMA in eutopic ESCs and ectopic ESCs treated with IL-33 or TGF-β1. D-F Cell viability (D) and migration …

Additional file 7: Supplementary Figure 3. Autocrine Effect of IL-33 on Stromal Cells. A-C. mRNA (A) and protein (B, C) expression of α-SMA in eutopic ESCs and ectopic ESCs treated with IL-33 or TGF-β1. D-F Cell viability (D) and migration …

Additional file 8: Supplementary Figure 4. Knockdown of ST2 and β-catenin Induced by siRNA were Confirmed by WB. A Protein expression of ST2 in EECs and 12Z cells treated by knocking ST2 by siRNA. B Protein expression of β-catenin in EECs a…

Additional file 8: Supplementary Figure 4. Knockdown of ST2 and β-catenin Induced by siRNA were Confirmed by WB. A Protein expression of ST2 in EECs and 12Z cells treated by knocking ST2 by siRNA. B Protein expression of β-catenin in EECs a…

Additional file 9.

Additional file 9.

Abstract Background As a dual-function metabolite, succinate has emerged in cell function and plays a key signaling role in linking mitochondrial function to other cellular functions. Succinate accumulation in the cytoplasm is commonly asso…

Abstract Background As a dual-function metabolite, succinate has emerged in cell function and plays a key signaling role in linking mitochondrial function to other cellular functions. Succinate accumulation in the cytoplasm is commonly asso…

Abstract Objectives Interleukin 33 (IL-33) is a crucial inflammatory factor that functions as an alarm signal in endometriosis (EMs). Epithelial-mesenchymal transition (EMT), a process related to inflammatory signals, intracellular reactive…

Abstract Objectives Interleukin 33 (IL-33) is a crucial inflammatory factor that functions as an alarm signal in endometriosis (EMs). Epithelial-mesenchymal transition (EMT), a process related to inflammatory signals, intracellular reactive…